Identifying neural signatures of Parkinson’s disease that predict decline in gait and postural control
Objective: To identify Parkinson’s disease [PD] specific patterns in the brain using a multi-modal neuroimaging design and use these to predict gait decline. Background: Gait…Prefrontal cortical activity and the control of walking in people with freezing of gait
Objective: To investigate the influence of freezing of gait (FoG) on automaticity of walking in people with Parkinson’s disease (PD). Background: A hallmark of healthy…Deficient Balance Mechanisms during Walking in People with Parkinson’s Disease
Objective: Investigate whether people with Parkinson’s disease (PD) have deficient balance mechanisms following visual perturbations during walking. Background: We recently showed that maintaining upright balance…Clinical and oculomotor correlates with freezing of gait in Chinese Parkinson’s disease
Objective: to investigate the clinical and oculomotor associations with freezing of gait (FOG) in Chinese Parkinson’s disease (PD). Background: FOG in PD has been reported…Central cholinergic activity and risk of falls in patients with Parkinson’s disease and freezing of gait
Objective: We evaluated whether changes in cholinergic function might be related to increased fall risk in PD patients with Freezing of Gait (FoG). Background: FoG…Abnormal frontal theta and beta oscillations during gait observation in Parkinson’s disease
Objective: To characterize the frontal oscillations during gait observation in Parkinson’s disease (PD) patients with (freezers) and without (non-freezers) freezing of gait. Background: Freezing of…Gait patterns may distinguish Parkinsonian patients with and without mild cognitive impairment: a data mining approach
Objective: To differentiate patients with Parkinson’s disease (PD) with and without mild cognitive impairment (MCI) using quantitative gait variables through a data mining approach Background:…Vascular white matter involvement in Idiopathic Normal Pressure Hydrocephalus: association with cognitive and motor impairment
Objective: To explore the relationship between vascular subcortical encephalopathy, ventricular dilation and clinical severity in idiopathic normal pressure hydrocephalus (iNPH). Background: The frequent co-occurrence of…The contribution of striatal dopamine to feedforward motor control during gait initiation in Parkinson’s disease
Objective: To establish the contribution of striatal dopamine to gait initiation in Parkinson’s disease. Background: Gait initiation (GI) is characterized by anticipatory postural adjustments (APAs),…Patterns of cortical thickness, surface area and subcortical volume in Parkinson’s disease patients with freezing of gait
Objective: To investigate the cortical thickness, surface area and subcortical volumes changes in the fronto-parietal cortices and subcortical structures, and to obtain a representative model…
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