Freezing of Gait in Parkinson’s Disease: Clinico-biochemical Observations
Objective: We aimed to compare motor and non-motor functions, 2D-spatiotemporal gait parameters and serum oxidative markers including catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA)…The Prevalence of Tandem Gait Abnormality in Parkinson’s Disease
Objective: To assess the prevalence of tandem gait abnormality in patients with Parkinson’s disease (PD), comparing Hoehn and Yahr (HY) stages 2 and 3. Background:…Cortical correlates of dual-task turning with and without freezing of gait
Objective: This study investigated the relationship between prefrontal cortex (PFC) activity and turning characteristics with and without a dual-task in in people with Parkinson’s disease…Anxiety influences the neural correlates associated with freezing of gait in Parkinson’s disease
Objective: To evaluate whether Anxious Freezers have altered brain activity during FOG episodes compared to Non-Anxious Freezers. Background: A growing amount of research has emphasized…Dopamine depletion impairs gait automaticity by altering cortico-striatal and cerebellar processing in Parkinson’s disease
Objective: Investigating the role of dopaminergic medication on the neural mechanisms underlying lower limb motor automaticity during fMRI in 23 patients with PD that were…Gait asymmetry in people with Parkinson’s disease is linked to reduced integrity of callosal sensorimotor regions
Objective: To evaluate the relationship between gait asymmetry and the integrity of the corpus callosum connecting sensorimotor cortical regions in people with idiopathic Parkinson’s Disease…Predicting the onset of freezing of gait: A longitudinal study
Objective: This prospective cohort study sought to examine longitudinal data spanning the transition period where PD patients developed FOG to identify symptoms that may precede…Gait disturbance and olfactory dysfunction is associated with central cholinergic dysfunction in early Parkinson’s disease
Objective: We hypothesis that olfactory dysfunction, could be an independent predictor of gait disturbance in early PD. Background: The pathophysiology of gait disturbance is not fully…Successful passive monitoring of early-stage Parkinson’s disease patient mobility in Phase I RG7935/PRX002 clinical trial with smartphone sensors
Objective: Smartphone-based assessments and sensors have the potential to enable remote, passive monitoring of gait and mobility in early-stage Parkinson’s disease (PD) patients. Such sensor…Objective identification of freezing of gait in Parkinson’s disease patients using a triaxial accelerometer
Objective: The aim of this study is to objectively detect and quantify freezing of gait (FOG) in Parkinson’s disease (PD) patients during everyday activities. Background:…
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