The differential role of subthalamic and nigral neurons in gait control in Parkinson´s disease patients
Objective: The aim of the study was to identify and characterize subthalamic (STN) and nigral (SNr) neurons showing gait-related activity changes. 12 Parkinson’s disease (PD)…Frailty status predicts falls in early Parkinson’s disease
Objective: To establish whether there is an association between frailty and falls in early Parkinson’s (PD). Background: PD is a syndrome in which postural control,…Visual assessment of dopamine transporter imaging in normal pressure hydrocephalus
Objective: We aimed to investigate detailed analysis for striatal dopaminergic depletion in idiopathic normal pressure hydrocephalus (iNPH) with visual assessment. Background: Variable degree of parkinsonism…Reverse phenotyping of a 3.3Mb loss of 8p11.21p11.1, including SLC20A2, lead to a diagnosis of primary familial brain calcification
Objective: To describe the clinical picture of a patient with a large deletion in band 8p11.21p11.1 including SLC20A2 and present a review of patients with a…Motor and Non-motor Features Predict Freezing of Gait in Parkinson’s Disease
Objective: To investigate and evaluate behavioral predictors of conversion to Freezing of Gait in Parkinson’s Disease (PD). Background: Freezing of Gait (FOG) has devastating consequences…Vascular parkinsonism: Clinical features and comparison with Parkinson’s disease
Objective: To define the clinical features of vascular parkinsonism (VP) and compare it to idiopathic Parkinson’s disease (iPD). Background: The main differential diagnosis of VP…The Association Between Inhibitory Control and Freezing of Gait Severity in Parkinson’s Disease
Objective: To investigate the relationship between inhibitory control and freezing of gait (FOG) severity in Parkinson’s disease (PD). Background: Inhibition deficits play a role in…Nucleotide repeats as genetic risk factors in a Swedish Parkinson’s disease cohort
Objective: To search for abnormal NRE in the following genes: ATXN2, ATXN3, CACNA1A, TBP, c9orf72, PRNP, POLG1A and TOMM40 in a Swedish PD cohort. Background:…Neuronal KIF5b deletion induces striatum-dependent locomotor impairments and defects in membrane presentation of dopamine D2 receptors
Objective: In this study we aim to elucidate the role of Kif5b motor subunit in the nigrostriatal pathway. We have generated different conditional knockout mice…Exploring novel diffusion-derived biomarkers in Parkinson’s disease Freezing of Gait
Objective: To explore the association between novel diffusion-derived structural imaging biomarkers and disease duration in Parkinson’s disease with freezing of gait (PD-FOG). Background: Increasing free-water…