Neural Correlates of Dual Task Touchscreen Performance in Parkinson’s Disease
Objective: To compare task-related brain activity during a touchscreen task in Parkinson’s disease (PD) patients and healthy controls (HC) in single (ST) and dual task…Transcranial magnetic stimulation target comparison identifies motor network reorganization associated with behavioral improvement in writer’s cramp dystonia
Objective: This study aims to reveal the motor network effects of repetitive transcranial magnetic stimulation (rTMS) in Writer's cramp (WC) subjects that correspond to behavioral efficacy.…Abnormal basal ganglia-related functional gradient in Parkinson’s disease
Objective: The aim of this research was to investigate the basal ganglia (BG)-related functional gradient alterations and the association between these brain dysfunctions and clinical…Reliability of neurophysiological and cerebral tremor features in Parkinson’s disease
Objective: We aim to assess the stability and intra-individual reliability of clinical, neurophysiological and neuroimaging Parkinson’s Disease (PD) tremor parameters. Background: The cerebello-thalamo-cortical circuit (CTC)…Classification of Parkinson’s disease using AI based on multi-modal brain MRI connectomics
Objective: To develop a novel artificial intelligence (AI) model using connectivity matrices derived from multi-modal brain magnetic resonance imaging (MRI) to aid diagnosis and subtyping…Longitudinal Structural and Functional Correlates of Progression in Isolated Rapid Eye Movement Sleep Behaviour Disorder
Objective: To identify progressive structural and functional imaging alterations in a longitudinal cohort of patients with isolated rapid eye movement sleep behavior disorder (iRBD). Background:…Progression of striatocortical dysfunction in Parkinson’s disease: a longitudinal combined PET and fMRI study
Objective: To investigate the longitudinal progression of striatal dopaminergic dysfunction and its consequences on functional connectivity (FC) networks and clinical progression in Parkinson's disease (PD)…Evidence of Central Autonomic Network dysfunction in orthostatic hypotension of Parkinson’s disease
Objective: To examine the contribution of the central autonomic network (CAN) to physiologic evidence of autonomic failure in Parkinson’s disease (PD). Background: Autonomic dysfunction, particularly…Clinical severity in Parkinson’s disease is determined by decline in cortical compensation
Objective: We tested whether inter- and intra-individual differences in clinical severity are determined by cortical compensation, and not just by basal ganglia dysfunction. Background: Motor…Understanding the Mechanisms of Brain Dysfunction when Performing the Mental Rotation Task (MRT) in Stage 1 and Stage 2 EOPD using brain imaging
Objective: Our aim is to understand MRT abnormalities in PD using fMRI and whether it can be used as a clinical marker for disease progression…
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