Distinct memory networks in Parkinson’s disease (PD) and Alzheimer’s disease (AD): Effects of APOE
Objective: As part of the Ontario Neurodegenerative Disease Research Initiative, we investigated group differences in functional connectivity within two distinct memory networks: posterior medial network…Deficient interhemispheric connectivity underlies movement irregularities in Parkinson’s disease
Objective: The aim of this study was to investigate whether impaired execution of drawing spirals relates to deteriorations in interregional connectivity. Background: Movement execution is…DO FREEZING OF GAIT AND GAIT AUTOMATICITY IN PARKINSON’S DISEASE SHARE THE SIMILAR NEURAL SUBSTRATE?
Objective: To verify if freezing of gait (FOG) in Parkinson’s disease (PD) and gait automaticity share a similar neural substrate. Background: FOG in PD may…Tremor in dystonia is associated with increased brain activity in the cerebellum and pallidum
Objective: To identify brain regions showing tremor-related activity in patients with dystonic tremor syndrome. Background: Dystonic tremor syndromes are highly burdensome and treatment is often…Resting-state connectivity predictors for prefrontal cortex activity during walking in Parkinson’s disease.
Objective: Investigating whether resting-state brain connectivity can predict prefrontal cortex activity (PFCA) during walking for patients with Parkinson's disease (PD) and reflect the benefits of…Aberrant dopamine transporter and functional connectivity patterns in LRRK2 and GBA non-manifesting carriers
Objective: We aimed to study the association between presynaptic striatal dopamine uptake and functional connectivity (FC) patterns among healthy first-degree relatives of PD patients with…An Eyes-Open/Closed Manipulation Reveals Disrupted Default Mode Network Connectivity in Parkinson’s Disease and REM Sleep Behavior Disorder
Objective: To spatially localize disruptions in default mode network connectivity in prodromal and diagnosed Parkinson’s disease relative to controls. Background: Previously our research team reported…Altered functional activity of the motor system related to ankle and hand movements in Parkinson’s disease: insights from functional MRI
Objective: Examine functional magnetic resonance imaging (fMRI) activity during hand and foot force production tasks in Parkinson’s disease (PD). Background: Previous MRI studies in PD…Relationship Between Hyposmia and Olfactory Network Connectivity in Patients With Parkinson’s Disease
Objective: To examine resting-state functional Magnetic Resonance Imaging in a group of Parkinson’s Disease patients, used to characterize changes in functional connectivity of the olfactory…The neural correlates of dynamic balance control in Parkinson’s disease and freezing of gait
Objective: To investigate the neural correlates of postural control in Parkinson’s disease (PD) with and without freezing of gait (FOG) as compared to healthy older…
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