MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Familial neurodegenerative diseases"

  • 2018 International Congress

    Analysis of secondary causes in Fahr’s syndrome and whole exome sequencing in Fahr disease from Northeast China and South Korean

    G. Shen, B. Jeon, G. Nan, S. Park (Changchun, China)

    Objective: In this study, patients with Fahr syndrome were analyzed for etiology, and genetic testing was performed for patients with Fahr disease from Northeast China…
  • 2018 International Congress

    Clinical and genetic heterogeneity in portuguese patients with Hereditary Spastic Paraplegia

    I. Cunha, A. Brás, J. Ribeiro, C. Januário (Coimbra, Portugal)

    Objective: To characterize the demographic, clinical and genetic features of HSP and to define the phenotypic spectrum and genotype-specific differences. Background: Hereditary spastic paraplegia (HSP)…
  • 2018 International Congress

    Primary familial brain calcification – The impact of calcifications on the development of motor symptoms

    D. Alvarez-Fischer, C. Schiemenz, G. Mahlke, A. Keller, A. Westenberger, J. Erdmann, Z. Aherrahrou, C. Klein (Lübeck, Germany)

    Objective: The aim of the present study was to investigate whether the nigro-striatal system in a genetic mouse model of primary familial brain calcification (PFBC)…
  • 2018 International Congress

    A Randomized Trial of Deferiprone for Pantothenate Kinase-Associated Neurodegeneration

    T. Klopstock, F. Tricta, L. Neumayr, I. Karin, G. Zorzi, C. Fradette, T. Kmieć, B. Buechner, H. Steele, R. Horvath, P. Chinnery, A. Basu, C. Küpper, C. Neuhofer, P. Dušek, F. Zhao, F. Zibordi, N. Nardocci, C. Aguilar, S. Hayflick, M. Spino, A. Blamire, P. Hogarth, E. Vichinsky (Munich, Germany)

    Objective: To investigate whether treatment with the iron-chelating drug deferiprone (DFP) has benefit in patients with pantothenate kinase-associated neurodegeneration (PKAN), the most common form of…
  • 2018 International Congress

    Deep brain stimulation for monogenic Parkinson’s disease: A systematic review

    T. Kuusimäki, J. Korpela, E. Pekkonen, M. Martikainen, A. Antonini, V. Kaasinen (Turku, Finland)

    Objective: The aim was to systematically investigate the outcome of deep brain stimulation (DBS) in genetic Parkinson’s disease (PD) compared to the patients with documented…
  • 2017 International Congress

    Living with Ataxia in Ireland 2016–a nationwide survey of 130 Irish patients with inherited Ataxia

    P. Bogdanova-Mihaylova, R. Walsh, S. Murphy (Dublin, Ireland)

    Objective: To collect real-life data from a large cohort of patients with inherited ataxia in Ireland, with special attention to the individual ataxia-related healthcare resources…
  • 2017 International Congress

    Utility of ataxia gene panel testing in diagnosing inherited ataxia: evaluation of an Irish cohort

    P. Bogdanova-Mihaylova, R. Walsh, S. Murphy (Dublin 24,, Ireland)

    Objective: To evaluate the utility of gene panel testing in a population of patients with genetically undetermined ataxia attending the Irish National Ataxia clinic. Background:…
  • 2017 International Congress

    SPG7-related ataxia in the Irish National Ataxia Clinic cohort: case series

    P. Bogdanova-Mihaylova, S. Murphy, R. Walsh (Dublin, Ireland)

    Objective: To present comprehensive clinical, optical coherence tomography (OCT) and genetic findings on SPG7 –related cohort attending the National Ataxia Clinic in Ireland. Background: Hereditary…
  • 2017 International Congress

    Neuroferritinopathy pedigree in 2 families from India

    J. Kaur, G. Singh, B. Paul (Ludhiana, India)

    Objective: The abstract provides description of first case report of two Indian families with Neuroferritinopathy (NFT) pedigree. Background: NFT is a rare autosomal dominant movement disorder caused…
  • 2017 International Congress

    Genotype-phenotype correlations in Parkinson disease patients who carry mutations in the GBA gene.

    A. Thaler, T. Gurevich, A. Ezra, M. Kestenbaum, N. Giladi, A. Mirelman (Tel Aviv, Israel)

    Objective: To assess genotype-phenotype relationship between mild and severe GBA mutation carriers among patients with Parkinson's disease  Background: Mutations in the Glucocerebrocidase gene (GBA) are…
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