Saccadic Hypometria as a Biomarker of Longitudinal Change in MDS-UPDRS Part II and Axial Motor Subscores: Results from the Multicenter PALOMA Trial
Objective: To evaluate the relationship between longitudinal changes in saccadic hypometria and changes of clinically meaningful outcomes, specifically axial impairment and MDS-UPDRS Part II scores,…Relationship between automatic analysis of gait disorder and eye movement capture by AI and cognitive function in Parkinson’s disease
Objective: Gait disorder is a hallmark of Parkinson’s disease (PD), with mounting evidence linking gait to cognitive function in PD patients and eye movements serving…Unveiling Oculomotor Phenotypes in Parkinson’s Disease: A Multidimensional Clustering Analysis
Objective: To characterize distinct Parkinson’s Disease (PD) oculomotor phenotypes and evaluate their correlation with motor severity, cognitive function, and non-motor symptom (NMS) profiles using unsupervised…“Shaky Eyes”: an Unusual Case of Ocular Movement Disorder
Objective: To report an unusual video case of paroxysmal conjugate saccadic ocular oscillations and discuss the challenges in the diagnostic process differentiating ocular movement disorders.…Multiscale entropy: a New Oculomotor Measure of PSP.
Objective: The objective of this study was investigate whether multiscale entropy, a measure of complexity, when applied to the path of unconstrained eye movements could…Utilizing the 15-item modification of the PSPRS rating scale (mPSPRS-15) as the primary endpoint for future clinical trials in progressive supranuclear palsy
Objective: To compare the properties of PSPRS-28, mPSPRS-15, and the rPSPRS-10 and assess their utility as a primary endpoint in PSP trials. Background: Progressive supranuclear…Peripheral neuropathy in Autosomal Recessive Spinocerebellar Ataxia due to ANO10 mutation – Expanding the phenotypic spectrum
Objective: SCAR10/ Adult-onset autosomal recessive cerebellar ataxia is an exceptionally rare form of ataxia, caused by mutations in the ANO10 gene and the specific genotype–phenotypecorrelation…Oculomotor Abnormalities in Spinocerebellar Ataxia Type-12: A Functional Neuroimaging Study
Objective: This study aimed to investigate eye movements, specifically dysmetric saccades and cerebellar nystagmus, in Spinocerebellar Ataxia Type-12 (SCA12) using functional magnetic resonance imaging (fMRI)…Opsoclonus-Myoclonus Ataxia plus Demyelinating Neuropathy Syndrome in an uncommon type of Prostate Cancer, a Case Report
Objective: To present a unique case of adult-onset opsoclonus-myoclonus ataxia plus demyelinating neuropathy syndrome in a patient with large cell neuroendocrine prostate carcinoma with isolated…A Rare Case of Anti-Hu Opsoclonus-Myoclonus Syndrome after Immune Checkpoint Inhibitor Immunotherapy in a Patient with Small Cell Lung Cancer in Remission
Objective: To describe a case of anti-Hu/ANNA-1 Opsoclonus-Myoclonus syndrome (OMS) in a patient with small cell lung cancer (SCLC) after treatment with an immune checkpoint…
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