Safinamide and Rasagiline effect on motor fluctuation, sleep quality and daytime sleepiness in Parkinson’s Disease: A validated questionnaires study
Objective: This is an observational study aimed at evaluating the effect of Safinamide and Rasagiline on motor fluctuations, subjective sleep and daytime sleepiness in Parkinson’s…Clinical heterogeneity of excessive daytime sleepiness in Parkinson’s disease
Objective: To examine reasons and associated clinical features of excessive daytime sleepiness (EDS) in patients with Parkinson’s disease (PD). Background: Patients with EDS can divided…Progression of sleep disorders spectrum in Parkinson’s Disease: A 5 year clinical longitudinal study
Objective: To investigate longitudinal changes in the prevalence of different sleep disorders in the PPMI cohort of patients with Parkinson’s Disease (PD). Background: Sleep disturbances…Relationship between sleep profiles and clinical features in Parkinson’s disease
Objective: To document the prevalence of sleep disturbance and excessive daytime sleepiness (EDS) in Taiwanese Parkinson’s disease (PD) patients and to identify the risk factors…Excessive daytime sleepiness in Parkinson’s disease: risk factors and clinical associations
Objective: To examine the frequency and risk factors of excessive daytime sleepiness (EDS) in patients with PD and to determine relationships between EDS and another…Somnolence as untoward stimulation effect in subthalamic deep brain stimulation (STN DBS) for Parkinson’s disease (PD)
Objective: Excessive daytime sleepiness is a relatively common feature in PD. However, it has not been reported as a side effect of STN DBS. We…Istradefylline improves not only motor symptoms but also sleep disturbance, daytime sleepiness, and QOL of Parkinson’s disease patients.
Objective: This study analyzed the clinical effectiveness of istradefylline in terms of sleep disturbance in Parkinson’s disease (PD) patients. Background: A selective adenosine A2A receptor…The role of phosphodiesterase 4 in sleep disturbances in Parkinson’s disease
Objective: We aimed to assess the association between phosphodiesterase 4 (PDE4) expression and sleep disturbances in vivo using combined multimodal magnetic resonance imaging (MRI) and…Effectivity and safety of rotigotine transdermal patch on motor and cognitive dysfunctions in Parkinson’s disease with dementia and dementia with Lewy bodies
Objective: This study aimed to demonstrate effectivity and safety of rotigotine transdermal patch (RTP) on motor and cognitive dysfunctions in patients with Parkinson's disease with…J-FIRST: First-in-Japan observational study of Parkinson’s disease treatments and nonmotor symptoms
Objective: To clarify the clinical manifestations of nonmotor symptoms (NMSs) and identify factors affecting NMSs and quality of life (QOL) in Japanese patients with Parkinson's…
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