Real-World Clinical and Safety Outcomes from a Prospective, Multicenter Deep Brain Stimulation Registry of Essential Tremor Patients
Objective: Here, we evaluate on-going registry outcomes derived from patients implanted with directional Deep Brain Stimulation systems with Multiple Independent Current Control (MICC) technology for…Suvecaltamide Metabolites Are CaV3 Modulators and Contribute to Pharmacological Effect
Objective: To determine the potency-concentration relationships and combined pharmacological effects for suvecaltamide and its 2 active metabolites (JZZ05000034=M01, JZZ05000035=M02; total active moiety [TAM]). Background: T-type…Classification of Tremor and Myoclonus: An Explainable Machine Learning Approach
Objective: Providing a proof of concept for the classification of movement disorders using explainable machine learning applied to power spectra derived from accelerometry recordings. Background:…Increasing access to Deep Brain Stimulation for an underserved patient population: A retrospective cohort from an urban hospital in a diverse county in the USA.
Objective: To understand whether the presence of a Bilingual Movement Disorder specialist increases access to Deep Brain Stimulation (DBS) for an underserved patient population. Background:…Examining the association between adverse effects of magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy for essential tremor and structural connectivity using probabilistic tractography targets
Objective: We examine the relationship between adverse effects of MRgFUS thalamotomy in essential tremor (ET) patients and the structural connectivity of the ventral intermediate nucleus…A single centre retrospective study of dual target deep brain stimulation for clinically complex essential and dystonic tremor – a 5-year follow up
Objective: Measure efficacy of dual target deep brain stimulation in pharmaco-refractory tremors. Background: Tremor is characterised by involuntary rhythmic movement present in one or more…Connectomics of Chronic VIM vs Rescue VIM/VO Deep Brain Stimulation in Essential Tremor
Objective: This study aims to use connectomic analysis to determine the difference between fiber pathway activation in patients with ineffective VIM stimulation and effective VIM/VO…Worsening of Essential Tremor after SARS-CoV-2 infection: 1 year follow up.
Objective: To follow up on clinical and kinematic tremor features as well as non-motor symptoms, neuroimaging, and laboratory changes in a patient diagnosed with essential…Myotonic Dystrophy type 1 presenting as postural tremor
Objective: Description of a clinical case of extra-pyramidal features in a patient with myotonic dystrophy type 1. Background: Myotonic dystrophy type 1 (MD-1) is an…Association of fecal short-chain fatty acids with clinical severity and gut microbiota in Essential tremor and its differences from Parkinson’s disease
Objective: To investigate the fecal levels of short-chain fatty acids (SCFAs) in essential tremor (ET) patients, assess their relationships with clinical symptoms and gut microbiota,…
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