Acute Stimulation-Induced Ataxia From Thalamic Deep Brain Stimulation
Objective: To characterize stimulation-induced ataxia in Essential Tremor patients treated with VIM DBS. Background: In Essential tremor (ET) patients with medically refractory tremor, deep brain…A phase 2b, randomized, dose-response study of SAGE-324/BIIB124 for the treatment of essential tremor: KINETIC 2 trial in progress
Objective: The phase 2b KINETIC 2 trial is a double-blind, randomized, placebo-controlled, dose-response study designed to evaluate SAGE-324/BIIB124 (SAGE-324) for the treatment of patients with…Electrical stimulation of muscle afferents for tremor reduction in essential tremor patients
Objective: To describe the preliminary clinical results of a research project on electrical stimulation of muscle afferents to reduce tremor in patients with Essential Tremor…The Hidden Disease Burden and Treatment Experience of Patients with Essential Tremor: A Retrospective US Claims Analysis
Objective: To describe the attributes of patients with essential tremor (ET), associated comorbidities, and ET treatments using a US claims database. Background: ET is estimated…Fall prevention in patients undergoing Magnetic resonance-guided focused ultrasound thalamotomy (MRgFUS thalamotomy) for refractory essential tremor (ET)
Objective: To assess the efficacy of physiotherapy with fall prevention instructions in patients with refractory ET who underwent unilateral MRgFUS thalamotomy. Background: unilateral MRgFUS thalamotomy…Abnormal streamline density of the tremor network in tremor dominant Parkinson’s disease and Essential tremor plus syndrome
Objective: To evaluate streamline density (SD) of the basal ganglia-thalamocortical (BGTC) and cerebello-thalamocortical (CTC) network in tremor dominant Parkinson’s disease (TDPD) and essential tremor plus…Classical Machine Learning approaches to automate tremor detection from electrophysiological data
Objective: To detect tremor syndromes from electrophysiological signatures using classical machine learning techniques. Background: Electromyographic recordings combined with accelerometry data are widely used to measure…Non-motor symptom characteristics in patients with essential tremor
Objective: The objective of this study was to evaluate non-motor symptoms in essential tremor (ET) and compare those to healthy controls (HCs). Background: ET is…A Phase 2 Clinical Trial Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of PRAX-944 in Adults with Essential Tremor
Objective: We present preliminary findings from PRAX-944-221, a Phase 2a clinical trial evaluating efficacy, safety, tolerability, and pharmacokinetics of PRAX-944 in adults with essential tremor…Abnormal fractional anisotropy of the tremor network in tremor dominant Parkinson’s disease and Essential tremor plus syndrome
Objective: To evaluate alterations in fractional anisotropy (FA) of the basal ganglia-thalamocortical (BGTC) and cerebello-thalamocortical (CTC) network in tremor dominant Parkinson’s disease (TDPD) and essential…
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