Anti-tremor efficacy of Nabiximols (JZP378) in a rat Model of essential tremor
Objective: To assess the effect of acute and subchronic oral administration of nabiximols (JZP378), a complex botanical cannabinoid drug mixture with Δ9-tetrahydrocannabinol (THC) and cannabidiol…Asymmetry and side concordance of rest tremor and bradykinesia in patients with essential tremor
Objective: In the present study, we aimed to investigate the clinical and kinematic features of rest tremor and bradykinesia in patients with essential tremor (ET),…Testing for alcohol responsivity in familial essential tremor
Objective: In this study, we describe the alcohol response in our familial essential tremor cohort by employing the Knudsen-Lorenz-Deuschl test for alcohol responsivity outside its…Is there a common structural network for stimulation-induced dysarthria in subthalamic and thalamic deep brain stimulation?
Objective: To identify a common structural network for stimulation-induced dysarthria (SID) in thalamic deep brain stimulation (DBS) and DBS of the Nucleus subthalamicus (STN). Background:…Instability after MRIg-FUS thalamotomy: why does it appear?
Objective: To know the semiological characteristics and physiopathology of instability after thalamotomy with Magnetic Resonance image guided focused ultrasound thalamotomy (MRIg-FUS). Background: Gait instability is…Staged and simultaneous bilateral MRI-guided focused ultrasound treatment of essential tremor
Objective: The study aims to show that effective and safe bilateral MRgFUS treatment of ET is achievable. Background: Unilateral MRI-guided focused ultrasound (MRgFUS) thalamotomy reduces…Asymmetry of striatal dopaminergic function in essential tremor is associated with kinetic tremor asymmetry
Objective: To investigate possible dopaminergic pathophysiology of essential tremor (ET) by focusing on tremor asymmetry. Background: Essential tremor (ET) is considered a non-dopaminergic movement disorder.…Frequency coding mechanism of tremor in the cerebellar circuitry
Objective: Tremor is an involuntary rhythmic movement. However, the frequency-coding mechanism of tremor remains unknown. This study aims to identify such mechanism in the central…Relationship between bradykinesia and cognitive functions in patients with essential tremor
Objective: To investigate the association between bradykinesia, i.e., movement slowness, as objectively assessed with kinematic analysis, and cognitive functions in ET. Background: Bradykinesia in essential…Cognitive profile of essential tremor patients: Beyond the cerebellar cognitive affective syndrome
Objective: To describe the cognitive profile of essential tremor (ET) patients and gain insight into its pathophysiological process. Background: Nowadays, ET is considered as a…
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