Validation of the PREDIGT Score for the Incidence Rate of Parkinson disease
Objective: To assess the discriminative power of the PREDIGT formula for incident Parkinson disease (PD). Background: The inability to predict the incidence rate of PD…Maladaptive Nigrovagal Neuronal Plasticity Causes Ascending Alpha-Synucleinopathy in a Novel Environmental Toxin Based Rat Model of Parkinsonism
Objective: Test the hypothesis that unilateral chemogenetic inhibition of the nigrovagal pathway in the subthreshold Paraquat (P) + dietary lectin (L) exposure rat model of…Oculomotor Behavior in Healthy Caribbean: Does it reflect an increased vulnerability to degenerative Parkinsonism?
Objective: To investigate the impact of environmental factors on eye movement performances in two populations composed of carefully selected healthy subjects with strikingly different ethnic…Occupational trichloroethylene exposure and Parkinson’s disease risk
Objective: To assess whether occupational exposure to the solvent trichloroethylene (TCE) is associated with increased risk of Parkinson's disease (PD). Background: Severe solvent intoxication can…Two-year prospective study reveals that gut dysbiosis predicts progression of Parkinson’s disease
Objective: This study is to examine whether intestinal microbiota correlate with pathology progress of PD severity and change of gut microbiota for 2 years. Background:…Exposure to bifenthrin contributes to Parkinson’s disease in mouse model
Objective: To explore the relationship between pyrethroid bifenthrin and Parkinson’s disease on mouse model. Background: Pyrethroid is now widely used on account of its high…Serum levels of polychlorinated biphenyls, CYP2B6 and neurodegenerative disease in the Faroe Islands
Objective: To investigate genetic variability in CYP2B6, PCB levels and Parkinson's disease in the Faroese. Background: Polychlorinated biphenyls (PCBs) are persistent man-made highly toxic pollutants…Long-term incidence of Parkinson’s disease in rural areas of Finland
Objective: To investigate possible long-term changes in the incidence of Parkinson's disease (PD) in rural regions. Background: Living in rural areas has long been suspected…Rotenone and Parkinson’s disease (PD): Effect modification by membrane transporter variants
Objective: Determine whether variants in the xenobiotic efflux membrane transporter p-glycoprotein gene (ABCB1, p-gp, MDR1) modify the association of rotenone and PD. Background: Use of…Association of UV radiation with Parkinson’s disease incidence: A nationwide French ecologic study
Objective: Using ultraviolet B (UV-B) as a surrogate for vitamin D levels, we conducted a nationwide ecologic study in France in order to examine the…
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