MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Dystonia: Treatment"

  • 2026 International Congress

    Rare Observations of Sustained Symptomatic Improvement with Botulinum Toxin Type A Injections in Facial and Cervical Dystonia: Case Series

    N. Rozenberg, G. Yahalom, D. Segal, L. Barski, V. Livneh, A. Ezra, R. Alcalay, T. Gurevich (Tel Aviv, Israel)

    Objective: To describe prolonged improvement in patients with involuntary facial and cervical movements after BTX-A therapy. Background: ​​​​​​ Botulinum toxin type A (BTX-A) treatment is considered…
  • 2026 International Congress

    Muscarinic receptor antagonism beyond M4 is required for efficacy in a preclinical model of dystonia and Parkinson’s disease

    M. Rogge, J. Thornton, T. Engber, S. Engel, J. Dunn (Cambridge, USA)

    Objective: To inform the target activity profile of future movement disorder therapies, pre-clinical studies quantified the contribution of M4 receptor occupancy (M4RO) to reversal of…
  • 2025 International Congress

    Adherence with Digital Outcome Measures in Focal Dystonias

    A. Tingin, P. Reyes, F. Qeadan, L. Wright, G. Kilic-Berkmen, S. Bellows, S. Fox, D. Martino, J. Feuerstein, A. Wagle Shukla, A. Deik, R. Barbano, B. Berman, J. Perlmutter, H. Jinnah, S. Pirio Richardson (Albuquerque, USA)

    Objective: We assessed patient adherence with an app-based patient-centered outcome (PCO) tool for focal dystonia in a prospective study to determine the impact of dystonia…
  • 2025 International Congress

    Challenges in Airway Management after Deep Brain Stimulation in DYT1 Dystonia: a Case Report

    CE. Wang, CF. Hu, YH. Chen, YF. Sung (Taipei City, Taiwan)

    Objective: To highlight the challenges in upper airway management following deep brain stimulation (DBS) in patients with severe, medically refractory DYT1 dystonia and to emphasize…
  • 2025 International Congress

    National Survey of DYT/PARK-GCH1 (Segawa Disease) in Japan

    K. Hoshino, M. Kawai, Y. Nagao, M. Nozaki, Y. Yatomi, Y. Hirano, M. Fukumizu, I. Kawahata, H. Shintaku, K. Kimura, M. Hayashi (Osaka, Japan)

    Objective: To clarify clinical features of Segawa Disease (SD) in Japan. Background: Prof Segawa discovered SD 50 years ago, and GCH-1 gene mutations were linked…
  • 2025 International Congress

    Long-Term Therapeutic Effect of Botulinum Neurotoxin Type A (BoNT-A) in Cervical Dystonia: A Case Series.

    R. Lopez-Castellanos, R. Lopez-Contreras (Boston, USA)

    Objective: To evaluate the long-term therapeutic effect of Botulinum neurotoxin type A (BoNT-A) in cervical dystonia. Background: Cervical dystonia is the most common adult-onset focal…
  • 2025 International Congress

    The Vodka Trial: Clinical and Genetic Characteristics of Alcohol Responsiveness in Laryngeal Dystonia

    L. O'Flynn, A. Domingo, A. Hamzehei Sichani, A. Nishiyama, M. Hincher, R. Yadav, L. Ozelius, K. Simonyan (Boston, USA)

    Objective: To determine the objective characteristics of alcohol responsiveness in laryngeal dystonia (LD) using a standardized alcohol challenge test and genetic testing. Background: LD is…
  • 2025 International Congress

    GPi-DBS responsive laryngeal dystonia in SGCE myoclonus-dystonia

    S. Nagaratnam, D. Wilson, L. Williams, S. Xi, L. Natsis, J. Mcmaster, N. Mahant (Westmead, Australia)

    Objective: To describe a case of DBS-responsive laryngeal dystonia in the setting of myoclonus-dystonia secondary to e-sarcoglycan (SGCE) mutation. Background: DBS is emerging as a…
  • 2025 International Congress

    Understanding Family and Clinician Perspectives on Treatment Decision-Making for Acute Dystonia Exacerbations in Children

    L. Vogt, A. Leblanc-Millar, S. Breitbart, N. Al Azri, A. Fasano, K. Nelson, C. Gorodetsky (Toronto, Canada)

    Objective: Primary: To identify factors influencing the decision to provide acute pharmacological treatment for dystonia exacerbations in hospitalized pediatric patients. Secondary: To assess the alignment…
  • 2025 International Congress

    Development and Testing of a Smartphone Application to Capture Patient-Centered Outcome (PCO) Measures for Dystonia

    P. Reyes, A. Tingin, B. Berman, S. Schneider, J. Hieshetter, K. Kuman, G. Kilic-Berkmen, L. Wright, F. Qeadan, J. Perlmutter, H. Jinnah, S. Pirio-Richardson (Richmond, USA)

    Objective: Develop a smartphone application to collect patient-centered outcome (PCO) measures for dystonia. Background: PCO measures tailored for each major adult-onset focal dystonia subtype (Cervical…
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