Co-contractions as a Biomarker for DBS Efficacy in Dystonia
Objective: Deep brain stimulation of the globus pallidus interna (GPi-DBS) is a treatment option for medication-refractory dystonia. However, the clinical outcome after DBS-GPi is variable,…Short and long-term cental action of botulinum neurotoxin treatment in laryngeal dystonia
Objective: To investigate short- and long-term central effects of BoNT treatment on brain function in patients with laryngeal dystonia (LD). Background: LD is an isolated…C-SURF: DBS programming using probabilistic maps as an efficient new approach to treat patients with dystonia: the results of a feasibility study.
Objective: To evaluate the clinical potential of a novel computer-guided prediction of optimal stimulation settings for pallidal DBS for the treatment of motor symptoms of…A Double Blind, Placebo Controlled, Crossover Study of Incobotulinumtoxin-A in Musician’s Focal Hand Dystonia
Objective: To determine the safety and efficacy of incobotulinumtoxin-A (BoNT) in musician’s dystonia. Background: Few published trials of BoNT in upper limb task-specific dystonia are…The impact of lockdown due to the COVID-19 pandemic on Asian cervical dystonia patients treated with Botulinum toxin injections
Objective: To explore the effect of postponement of BoNT injections on symptoms and quality of life (QoL) in patients with CD during COVID-19 related lockdowns.…Treatment of cervical dystonia using shorter incobotulinumtoxinA injection intervals improves patient-reported outcomes in those with inadequate benefits from standard intervals
Objective: To assess the impact of 2 different injection schedules of incobotulinumtoxinA on patient-reported assessments in cervical dystonia (CD). Background: There is individual variation in…Deep Brain Stimulation for Dystonia: A Single-center Experience
Objective: To report on deep brain stimulation (DBS) outcomes in dystonia and related movement disorders at Mass General Brigham (MGB) hospitals. Background: Dystonia is a…Tele-yoga for individuals with cervical dystonia: A pilot study
Objective: The objective of this study was to investigate the implementation, feasibility, and safety of a one-on-one tele-yoga intervention for individuals with cervical dystonia (CD).…DEEP BRAIN STIMULATION RESPONSE IN SIBLINGS WITH KMT2B DYSTONIA
Objective: To report two cases of adult-onset KMT2B related dystonia treated with pallidal deep brain stimulation (DBS). Background: KMT2B gene mutations have been described as…A Phase 3 Trial Evaluating the Efficacy, Duration of Effect, and Safety of DaxibotulinumtoxinA for Injection in the Treatment of Cervical Dystonia
Objective: To evaluate the efficacy and safety of two doses of DaxibotulinumtoxinA for Injection (DAXI) vs placebo for treatment of cervical dystonia (CD). Background: DAXI…
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