Istradefylline therapy for PD plus oromandibular dystonia
Objective: To clarify the dopaminergic system link between parkinson's disease (PD) and oromadibular dystonias (OMDy) co-occur, and the effect of istradefylline (IST) therapy. Background: OMDy are…Novel utilization of deep brain stimulation in the pedunculopontine nucleus for treatment of childhood-onset dystonia
Objective: Investigate the efficacy of deep brain stimulation (DBS) in the pedunculopontine nucleus (PPN) for the treatment of dystonia in pediatric patients. Background: Deep brain…DystoniaBoTXNet: A Deep Learning Platform for Predictive Outcome of Botulinum Toxin Treatment in Isolated Dystonia
Objective: To develop and validate an objective measure of the botulinum toxin treatment outcome in isolated dystonia. Background: Dystonia is characterized by abnormal, often painful,…Overnight stimulation: a new rescue strategy for deep brain stimulation-induced bradykinesia in dystonia?
Objective: We report the serendipity case of overnight stimulation for the management of stimulation-induced bradykinesia in two patients with generalized dystonia and clinically-effective pallidal deep…Theta-burst Cycling for Deep Brain Stimulation
Objective: To test the clinical efficacy of rapid-cycling deep brain stimulation (DBS) in children and young adults with dystonia. Background: Cycling of DBS for variable…The role of intraoperative electrophysiological monitoring in implanting globus pallidus internus electrodes in patients with dystonia
Objective: The first aim was to compare the preplanned GPi electrode neuroradiological trajectory with the final trajectory selected after electrophysiological monitoring. The second aim was…Development of a patient journey map for people living with cervical dystonia
Objective: As part of the ongoing European Reference Networks for Rare Neurological Diseases (ERN-RND) program, we aimed to develop a cervical dystonia patient journey map…Deep Brain Stimulation in Woodhouse Sakati Syndrome:A Single Institution Retrospect Analysis
Objective: Evaluation of clinical response in patients with WSS-associated generalized dystonia following DBS to GPI Background: Woodhouse–Sakati syndrome (WSS) is a rare autosomal recessive disease,…Occlusal Stabilization Appliance on treatment of cervical dystonia
Objective: To evaluate the effect of occlusal stabilization appliance on cervical dystonia. Background: Cervical dystonia is a contraction of the neck muscles that causes movement…Deep Brain Stimulation in Generalized Dystonia Caused by PRKRA Mutation
Objective: Dystonia is a hyperkinetic movement disorder with a complex pathophysiology. The medical treatment includes pharmacological treatment, including botulinum toxin (BoNT), which is considered the…
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