Pallidal firing rate and alpha oscillations correlate with the severity of clinical symptoms in patients with dystonia
Objective: To examined how pallidal activity correlates with symptom severity across dystonic patients. Background: The internal segment of globus pallidus (GPi) is the most common…Exploring Local Field Potential changes in Dystonic Camptocormia.
Objective: To describe a novel technology for detection of local field potentials in bilateral GPi-DBS to identify local field potential biomarker changes in dystonic camptocormia.…Dystonic tremor and ataxia as presenting symptoms of multiple sclerosis
Objective: Introduction Tremor in multiple sclerosis (MS) has traditionally been thought to be a feature of advanced disease and pathophysiology of MS tremor is known…Is Generalized and Segmental Dystonia Accompanied by Impairments of the Dopaminergic System?
Objective: To investigate functional dopaminergic impairments in dystonia, we compared patients with dystonia and Parkinson’s disease (PD) with normal controls using neuromelanin-sensitive magnetic resonance imaging…Pallidal single unit activity in cervical dystonia patients with unilateral deep brain stimulation
Objective: The aim of the current study is to characterize the neuronal activity of the pallidal area which gives the best benefit following unilateral deep…Multifractal spectrum width of pallidal activity correlates with dystonic severity
Objective: To examined whether multifractal properties of pallidal activity correlate with dystonic symptom severity across patients. Background: The internal segment of globus pallidus (GPi) is…Neural Signals in the Cerebellar Nuclei Gate the Manifestation of Dystonia-Associated Symptoms in Mice
Objective: Define the differences in electrophysiological signatures of cerebellar output between mouse models of dystonia with diverse severity and manifestation. Background: Dystonia is heterogeneous movement…Distinct patterns of dyskinetic and dystonic features following D1 or D2 receptor stimulation in a mouse model of parkinsonism
Objective: We set out to compare patterns of dyskinetic behaviours induced by the systemic administration of L-DOPA and D1 or D2 receptor (D1R, D2R) agonists…Surround inhibition (SI) in the human motor system during real life motor tasks.
Objective: To assess motor SI during real life motor tasks. Background: SI is a neurophysiological mechanism in the human nervous system that focuses neuronal activity…Promising Biomarkers for Task Specific Dystonia
Objective: To test the sensitivity, specificity, reproducibility and reliability of two neurophysiologic variables using transcranial magnetic stimulation (TMS) as potential diagnostic biomarkers of task specific…
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