Chronic striatal cholinergic agonist infusion as a model of dystonia
Objective: The objectives of this work were to create a primate model of dystonia based on striatal infusion of a muscarinic agonist (oxotremorin), and to…Structural and Functional Brain Alterations in Laryngeal Dystonia: A Coordinate-Based Activation Likelihood Estimation Meta-Analysis
Objective: Efforts to understand laryngeal dystonia (LD) pathophysiology using neuroimaging techniques have demonstrated altered brain structure and function in patients compared to healthy controls1-5. However,…Task-Based Functional Imaging in Task-Specific Focal Dystonia during Dystonia-Related and -Unrelated Tasks
Objective: To use task-based functional magnetic resonance imaging [fMRI] to examine body region-specific sensorimotor changes with the long-term goal of identifying potential unifying pathophysiological fMRI features…GABA in the Basal Ganglia Tracks Motor Severity and Response to BoNT Treatment in Cervical Dystonia
Objective: Determine if GABA and glutamate levels within sensorimotor network nodes correlate with symptom severity in cervical dystonia (CD) and are altered by botulinum neurotoxin…Abnormal brain iron metabolism influences neural function in isolated laryngeal dystonia
Objective: To investigate iron accumulation as a pathophysiological signature of laryngeal dystonia (LD) and assess the abnormal influence of iron on neural activity within the…Neural Signatures of Laryngeal Dystonia during Asymptomatic Tasks of Sequential and Learned Finger-Tapping
Objective: To investigate brain activity in laryngeal dystonia (LD) patients compared to healthy controls during asymptomatic motor tasks of sequential and learned finger-tapping, as well…Writing dysfluency associates with basal ganglia network dysfunction in writer’s cramp dystonia
Objective: The primary objective of this study was to identify brain regions associated with behavioral measures of dystonia in a specific subtype called writer’s cramp…Two Cases of Moyamoya Syndrome-Associated Chorea and Dystonia
Objective: To report on two cases of mixed movement disorder presentation of chorea and dystonia due to moyamoya syndrome for which one case was successfully…Temporal prediction in cervical dystonia
Objective: To explore temporal prediction ability as a novel pathophysiological framework in cervical dystonia. Background: The ability to build temporal prediction (TP) is a highly…Deep Brain Stimulation Duration and Changes in Basal Ganglia Excitatory/Inhibitory Balance in Children and Young Adults with Dystonia
Objective: We sought to explore associations between basal ganglia aperiodic signals and time since deep brain stimulation (DBS) implantation in children and young adults with…
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