Exploring the neurophysiology of cervical dystonia using TMS-EEG
Objective: To probe cortical excitability and inhibition in primary motor cortex and supplementary motor area (SMA) in cervical dystonia Background: Cervical Dystonia (CD) is characterized…Brainstem connection of Writer’s cramp: Electrophysiological correlates
Objective: In this study, we explored the involvement of brainstem in Writer’s cramp (WC) patients through pre-pulse inhibition of blink reflex and Start-React paradigm. Background:…Dystonia-like phenotype in a DYT1 rat model after peripheral trauma
Objective: Establishment and characterization of a DYT1 rat model with dystonia-like movements after sciatic nerve crush injury. Background: Penetrance of DYT1 dystonia is markedly reduced…Botulinum toxin A injections changes sensorimotor network activations in cervical dystonia to state more related to physiological condition
Objective: To evaluate botulinum toxin A (BoNT-A) effectiveness on network in sensorimotor circuits. Background: Involvement of many cerebellar structures, such basal ganglia, thalamus, cerebellum, premotor…Effects of cerebellar theta-burst stimulation on arm and neck movement kinematics in patients with focal dystonia
Objective: To investigate the influence of the cerebellum on the motor cortex in primary focal dystonia using cerebellar continuous theta-burst stimulation (cTBS) and to evaluate…Sensory gating and inhibition in dystonia
Objective: By performing an extensive evaluation of neurophysiological measurements accounting for inhibitory mechanisms within the S1, we aim to find if a central nervous system…Dystonia after peripheral nerve injury in DYT1 transgenic rats
Objective: To trigger a dystonic phenotype in a non-dystonic rat DYT1 model by inducing a peripheral nerve injury and to describe a new clinical scoring…Digitally captured Archimedes spiral indices correlate with clinical assessment of dystonia severity
Objective: To determine whether digitized spiral analysis captures severity of dystonia in comparison to motor scores from the clinical gold standard, the Burke-Fahn-Marsden rating scale…Robust sensorimotor deficits in a knock-in mouse model of primary torsion dystonia
Objective: The aim of present study was to (1) generate more powerful tests to detect robust behavioral alterations in the DYT1 knock-in mouse model of…A dynamic causal model of the superior colliculus: Inhibitory activity increases with the temporal discrimination threshold
Objective: To investigate if abnormalities observed in the putamen of unaffected first-degree relatives (of cervical dystonia patients) with abnormal temporal discrimination thresholds (TDT) are a…
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