Cervical dystonia – changes in resting state cerebellar connectivity induced by botulinum toxin
Objective: The aim of our study was to compare the connectivity between large-scale resting state networks and the cerebellum before and after treatment initiation. Background:…Disease Modeling of DYT1 Using Patient Induced Pluripotent Stem Cells
Objective: To create a resource of induced pluripotent stem cells (iPSCs) as models for exploring mechanisms of pathogenesis in DYT1 dystonia. Background: DYT1 an autosomal…Can cerebellar dysfunction help differentiate idiopathic from functional cervical dystonia?
Objective: This study investigated cerebellar function in patients with primary cervical dystonia (CD) and patients with presumed functional dystonia, with the intention to both clarify…Optimization of Region of Interest Analysis of the Superior Colliculus for Improved Activation Detection in Cervical Dystonia
Objective: Optimization of Region of Interest (ROI) Analysis of the Superior Colliculus for Improved Activation Detection in Cervical Dystonia Background: Cervical dystonia (CD) is a…Prevalence and Correlates of Anxiety & Depression in Cervical Dystonia
Objective: Our aim was to assess the prevalence and severity of mood disorder in our Cervical Dystonia population attending the botulinum toxin clinic and to…Neuronal responses of pallidal and cerebellar receiving thalamic nuclei to neck exertion in cervical dystonia patients
Objective: The goal of the study was to find differences in spontaneous and neck-related activity of pallidal and cerebellar receiving thalamic nuclei in patients with…Start React Paradigm In Patients With Cervical Dystonia
Objective: Compare StartReact paradigm in cervical dystonia (CD) patients compared to matched healthy participants. Background: The voluntary response to vestibular stimulation is enhanced in CD…Abnormal cerebellar learning in cervical dystonia
Objective: This study was conceptualized to asses if patients with cervical dystonia (CD) exhibit deficits in cerebellar function tested by motor adaptation and motor sequence…Peripheral trauma elicits a dystonic phenotype in a DYT1 transgenic mouse model
Objective: To induce a dystonic phenotype in DYT1 (hΔGAG3) mice through peripheral trauma in order to analyze metabolic and structural alterations in the striatum. Background:…Disease Modeling of Lesch-Nyhan Disease Using Induced Pluripotent Stem Cells
Objective: To create a resource of induced pluripotent stem cells (iPSCs) as models for exploring mechanisms of pathogenesis in Lesch-Nyhan disease (LND). Background: LND is…
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