Protocol for Cerebellar Deep Brain Stimulation in Children and Young Adults with Dyskinetic Cerebral Palsy: Combined N-of-1 trials to Assess Safety and Efficacy
Objective: This study seeks to alleviate severe movement and tone disorders in cerebral palsy (CP) through chronic neuromodulation using deep brain stimulation (DBS), targeting motor…Motor, epileptic, and developmental phenotypes in genetic disorders affecting G-protein coupled receptor signaling and cAMP metabolism
Objective: To provide a detailed clinical characterization of genetic disorders affecting G-protein coupled receptor signaling and cAMP metabolism Background: Genetic disorders affecting G-protein coupled receptor (GPCRs) signaling…Effect of bilateral pallidal stimulation on quality of life of pediatric patients with dyskinetic cerebral palsy (STIM-CP): A prospective single-arm multicenter study with a subsequent randomized double-blind crossover phase
Objective: STIM-CP is a prospective single-arm multicenter study to investigate the effects of deep brain stimulation of the globus pallidus internus (GPi-DBS) in pediatric patients…Spectrum of Movement disorders and Correlation with Functional Status in Children with Cerebral Palsy
Objective: We sought to detail the spectrum of movement disorders (MD) among children with cerebral palsy (CP) and assess impact on functional status. Background: Movement…Thalamic Deep Brain Stimulation for Acquired Dystonia in Children and Young Adults: A Phase I Clinical Trial
Objective: To evaluate preliminary efficacy and safety of bilateral ventralis oralis posterior (VOP) deep brain stimulation (DBS) for the treatment of acquired dystonia in children…Deep brain stimulation matters in pediatric neurology – single-center experience
Objective: This study is to review our single-center experience with deep brain stimulation (DBS) in pediatric patients with dystonia. Background: Deep brain stimulation (DBS) is…Pilot evaluation of pseudoelastic orthoses for supporting motor control in children with secondary dystonia and dyskinesia
Objective: The study reports preliminary observations on the use of orthotic devices with nonlinear spring properties prescribed with the aim to stabilise posture and improve…Localization of basal ganglia and thalamic damage in dyskinetic cerebral palsy
Objective: To quantitatively consolidate published reports of deep grey matter injury in cerebral palsy to determine the patterns of injury associated with dystonia and dyskinesias.…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.