Phenytoin Intoxication Masquerading as Generalized Chorea: A Case of Iatrogenic Double-Prescribing
Objective: To report a rare case of phenytoin-induced generalized chorea resulting from inadvertent medication duplication across multiple healthcare facilities, highlighting a preventable cause of acute…Effectiveness of Switching from Levodopa-Carbidopa Intestinal Gel to Levodopa-Carbidopa-Entacapone Intestinal Gel in Patients with Refractory Biphasic and Peak-of-Dose Dyskinesia
Objective: To evaluate the clinical benefit on motor complications of transitioning from levodopa-carbidopa intestinal gel (LCIG) to levodopa-carbidopa-entacapone intestinal gel (LECIG) in a cohort of…Subthalamic Beta Sub-band Composition and Gamma Dynamics Across Medication and Stimulation States in Parkinson’s Disease
Objective: To examine how levodopa pharmacodynamics and therapeutic deep brain stimulation (DBS) shape beta sub-band composition and gamma oscillations in the subthalamic nucleus (STN), and…Levodopa-Carbidopa Intestinal Gel Infusion Therapy in Advanced Parkinson’s Disease: Extension Study of Long-term outcomes of Single Centre experience
Objective: evaluate the long-term outcomes of levodopa-carbidopa intestinal gel (LCIG) infusion in patients with advanced PD with motor fluctuation in one centre Background: Levodopa-carbidopa intestinal…Efficacy and Safety of Mesdopetam (IRL790) for Levodopa Induced Dyskinesia in Parkinson’s Disease: A Meta analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy and safety of mesdopetam compared with placebo for levodopa‑induced dyskinesia (LID) in Parkinson’s disease (PD). Background: Mesdopetam (IRL790) is a…Sensor-based quantification of dyskinesia in Parkinson’s Disease: supervised vs unsupervised settings
Objective: To investigate whether sensor-derived metrics can quantify dyskinesia in Parkinson’s disease (PD), and to compare supervised and unsupervised assessments. Background: Dyskinesia is a common…Safer AI Dosing Recommendations in Parkinson’s Disease Through Uncertainty-Adaptive Prediction
Objective: To develop and validate a uncertainty-adaptive AI framework to improve the safety and clinical utility of levodopa dose predictions by explicitly flagging high-risk, ambiguous cases…Predictors of Levodopa-Induced Dyskinesia in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To systematically evaluate clinical, biomarker, and treatment-related predictors of LID in patients with PD. Background: Levodopa-induced dyskinesia (LID) is a common complication of long-term…Early-Onset Parkinson’s Disease with Early Peak-Dose Dyskinesia: A Case Report
Objective: To present a case of early-onset Parkinson's disease (EOPD) in a 41-year-old male with good levodopa response but complicated by early development of peak-dose…All Left: A Case of Ipsilateral Stimulation Induced Dyskinesia
Objective: Stimulation induced dyskinesia is a known phenomenon in subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson’s disease. However, stimulation induced dyskinesia affecting the…
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