Neuroprotective effects of allicin microemulsion against intrastriatal rotenone and manganese induced Parkinsonism in rats
Objective: Allicin is flavonoid that possess neuroprotective potential but main impediment is its low bioavailability which was improved with microemulsion. The present study was framed…Predictors of Underlying Neurodegeneration in Drug-Induced Parkinsonism
Objective: To examine a cohort of Veterans with drug-induced parkinsonism (DIP) using [123I]Ioflupane single photon emission computed tomography (DAT-SPECT) to identify those with nigrostriatal degeneration…Inertial-sensor based full-body kinematics reveals an unstable gait with increased variability in patients with evidence of dopaminergic denervation with 123I-FP-CIT SPECT
Objective: Distinguish patients with and without dopaminergic denervation (as assessed by 123I-FP-CIT-SPECT – DaTscan) with Inertial-sensor full body kinematics (FBK) assessment. Background: The differential diagnosis…Comparing the effects of rosemary and selegiline on behavioral symptoms of Parkinson’s animal model in mice
Objective: Parkinson is from common disorders of central nervous system and the second disease in neurodegenerative diseases which occurs in 1% of people over the…Anti-parkinson effect of natural L-DOPA containing drug Mucuna pruriens against the rotenone induced rat model of Parkinson’s disease
Objective: The nanoherbaceutical formulation comprising natural L-DOPA from Mucuna pruriens against rotenone caused Parkinson's disease in rats to be prepared and evaluated. Background: Parkinson's disease…Smartphone-based gait assessment of psychiatric patients on neuroleptics
Objective: To characterize gait performance recorded from psychiatric patients on neuroleptics (PPN) and to compare it to Parkinson’s disease (PD) patients and healthy controls (HC).…Waiting and waiting on Dopamine transporter imaging in drug induced parkinsonism
Objective: We discontinued offending medications in DIP or unmasked parkinsonism patients and delayed taking DAT images for one month. Background: Drug induced parkinsonism (DIP) may…Formulations and evaluations of Intranasal Nose to Brain Delivery of Curcumin with resveratrol Nanoparticle for treatment of Parkisonism
Objective: Parkinson’s disease (PD) is a common neurodegenerative disease characterized by motor symptoms of tremor, rigidity, bradykinesia, and postural instability. Growing evidence indicates that resveratrol…Design, characterization and In vivo evaluation of intranasal delivery of levodopa loaded microspere for Parkinsonism
Objective: Levodopa is the drug of choice in the treatment of Parkinson's disease but it exhibits low oral bioavailability and very low brain uptake. The…Development Of Anti-Parkinsonism Poly Herbal Sustained Release Formulation Composed Of Potential Traditional Plant Extracts
Objective: Parkinsonism is one of the commonest neurodegenerative diseases, which is characterized by a selective and progressive degeneration of dopaminergic neurons, causing a series of…
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