MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Dopamine"

  • 2022 International Congress

    Presynaptic dopamine compartmentalization defects initiate auxilin-mediated parkinsonism

    D J. Vidyadhara, M. Somayaji, N. Wade, H. Zhao, S. Narayanan, J. Gupta, T. Lam, D. Sames, L. Greene, D. Sulzer, S. Chandra (New Haven, USA)

    Objective: To evaluate the pathogenic mechanisms for auxilin-mediated Parkinson’s disease (PD). Background: Auxilin participates in uncoating of clathrin-coated vesicles (CCVs), thereby facilitating synaptic vesicle (SV)…
  • MDS Virtual Congress 2021

    Is Generalized and Segmental Dystonia Accompanied by Impairments of the Dopaminergic System?

    J. Ikezawa, F. Yokochi, R. Okiyama, S. Kumada, M. Tojima, T. Kamiyama, T. Hanakawa, H. Matsuda, F. Tanaka, Y. Nakata, E. Isozaki (Fuchu, Japan)

    Objective: To investigate functional dopaminergic impairments in dystonia, we compared patients with dystonia and Parkinson’s disease (PD) with normal controls using neuromelanin-sensitive magnetic resonance imaging…
  • MDS Virtual Congress 2021

    Connectomic Analysis of SNc and VTA Projections to the Striatum and Cortex

    N. Handfield-Jones, A. Owen, A. Khan, P. Macdonald (London, Canada)

    Objective: To investigate the dopaminergic neural tracts of healthy individuals using Diffusion MRI on Human Connectome Project Data. Background: Classically, the DA system has been…
  • MDS Virtual Congress 2021

    The effects of acute administration of VMAT2 inhibitors on extracellular levels of dopamine, norepinephrine, 5-HT and histamine in the striatum and medial prefrontal cortex

    E. Adler, L. Magid, O. Even-Chen, S. Schmidt, I. Cope, J. Alexander, J. Kehr, A. Orbach (Netanya, Israel)

    Objective: To evaluate the effects of reversible VMAT2 inhibitors (deutetrabenazine, tetrabenazine and valbenazine) on extracellular levels of monoamines and their acidic metabolites in rat striatum…
  • MDS Virtual Congress 2021

    Istradefylline/L-DOPA combination therapy for Parkinson’s disease and blood markers of glycolytic energy homeostasis

    NAO. Kanzato, KO. Nakachi, MA. Hayashi, F. Kinjyo, W. Mizuta, SA. Mochizuki (Haebaru-Cho, Okinawa, Japan)

    Objective: To clarify the potential to preserve glycolytic energy homeostasis (GEH) with the Istradefylline combined to L-DOPA (IST-LD), and to prevent LD-induced weight loss and…
  • MDS Virtual Congress 2021

    OPTIMIPARK Questionnaire:a tool to optimize treatment in Parkinson´s disease.

    J. Máñez-Miró, F. Vivancos-Matellano, L. Vela-Desojo, R. Martinez-Fernandez, F. Alonso-Frech, N. Lopez-Aristegui, E. Balaguer-Martínez, J. Martinez-Castrillo, L. Lopez-Manzanares, P. Martínez-Martín (Madrid, Spain)

    Objective: To validate the OPTIMIPARK questionnaire as a tool to help the clinician in the adjustment of dopaminergic treatment in Parkinson´s disease(PD). Background: At early…
  • MDS Virtual Congress 2021

    Influence of Dopamine Transporter Gene Polymorphism on Wearing Off

    CE. Mantese, V. Altmann, A. Schumacher-Schuh, M. Hutz, CRM. Rieder (Porto Alegre, Brazil)

    Objective: To study the influence of Dopamine transporter gene polymorphism on Wearing off (WO) through 19 items wearing off questionnaire (WOQ-19) Background: The dopamine transporter…
  • MDS Virtual Congress 2021

    Parkinson’s Disease Medication Safety in the Inpatient Cohort of a Tertiary Centre

    A. Redmond, G. Richard, M. Penugonda, D. Bradley (Dublin 8, Ireland)

    Objective: Our study aimed to determine the accuracy of initial prescribing on hospital admission and the subsequent timing of administration of Parkinson’s disease (PD) medications…
  • MDS Virtual Congress 2021

    The responsiveness of arm swing to dopaminergic medication in Parkinson’s disease depends on task complexity

    E. Warmerdam, R. Romijnders, C. Hansen, M. Elshehabi, M. Zimmermann, F. Metzger, A. von Thaler, D. Berg, G. Schmidt, W. Maetzler (Kiel, Germany)

    Objective: The aim of this study is to analyse the responsiveness of arm swing during walking to dopaminergic medication in patients with Parkinson’s disease. Background:…
  • MDS Virtual Congress 2021

    Effects of dopaminergic medication on reinforcement learning in Parkinson’s disease depend on depressive symptoms

    J. Tichelaar, C. Sayali, R. Helmich, R. Cools (Nijmegen, Netherlands)

    Objective: To investigate the effect of depression and dopaminergic medication on reinforcement learning (RL) in Parkinson’s disease. Background: Dopaminergic medication in PD is known to…
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