Diabetes impact on nigrostriatal vulnerability in Parkinson’s Disease
Objective: aim of the study was to investigate whether diabetes mellitus influences nigrostriatal dopaminergic vulnerability in drug-naïve patients with early-stage Parkinson’s Disease (PD). Background: recently,…Differential effect of dopaminergic medication on smooth pursuit vs. saccadic eye movements Parkinson’s disease
Objective: To assess the effect of dopaminergic medication on eye movements in Parkinson’s disease (PD). Background: PD is the second most common neurodegenerative disease, characterised…In silico electrophysiology study reveals the modulating role of calcium channel on Subthalamic nucleus neuronal cells towards Parkinson’s disease
Objective: The pathogenesis of Parkinson's Disease (PD) is associated with electrical firing patterns of the subthalamic nucleus (STN) neuronal cells. As the dysfunction of the…Impact of dopamine replacement therapies on MDS-UPDRS II
Objective: To estimate the longitudinal effect of different dopamine therapies on the Movement Disorder Society-Sponsored Unified Parkinson's Disease Rating Scale Part II (MDS-UPDRS II) among…Dopaminergic Denervation as Predictors of Axial Dysfunction in Parkinson’s Disease
Objective: We aimed to assess the usefulness of dopamine binding scores as predictors of walking and balance problems and freezing of gait (FoG) in PD.…EFFECTS OF DOPAMINERGIC MEDICATION ON REACTIVE AND PROACTIVE INHIBITORY CONTROL
Objective: In this study, we aim to address the effects of dopaminergic treatment (DT) on the two domains of motor inhibition [1], i.e., reactive (the…Remission of Gilles de la Tourette Syndrome Following Dehydration
Objective: To assess the beneficial and adverse effects of heat on a man with Gilles de la Tourette Syndrome (TS) Background: The effect of heat…Dopaminergic Denervation as Predictors of Falls in PD Patients
Objective: We aimed to predict fall risk in PD patients using SBR data obtained from PPMI. Background: While dopamine is currently considered to be the…Continuous circadian intracerebroventricular administration of anaerobically preserved dopamine greatly reduces severe L-dopa-related complications in Parkinson’s disease
Objective: We aim to demonstrate the safety and efficacy of continuous circadian intracerebroventricular (i.c.v.) administration of anaerobic-dopamine (A-dopamine) to reduce the L-dopa-related complications (LDRC) in…The agreement between automated and expert FOG annotations during an at-home protocol: influence of dopaminergic medication and task
Objective: To investigate agreement between a recent automated FOG detection algorithm and expert video ratings, and the influence of dopaminergic medication and task context. Background:…
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