Diabetes impact on nigrostriatal vulnerability in Parkinson’s Disease
Objective: aim of the study was to investigate whether diabetes mellitus influences nigrostriatal dopaminergic vulnerability in drug-naïve patients with early-stage Parkinson’s Disease (PD). Background: recently,…Differential effect of dopaminergic medication on smooth pursuit vs. saccadic eye movements Parkinson’s disease
Objective: To assess the effect of dopaminergic medication on eye movements in Parkinson’s disease (PD). Background: PD is the second most common neurodegenerative disease, characterised…In silico electrophysiology study reveals the modulating role of calcium channel on Subthalamic nucleus neuronal cells towards Parkinson’s disease
Objective: The pathogenesis of Parkinson's Disease (PD) is associated with electrical firing patterns of the subthalamic nucleus (STN) neuronal cells. As the dysfunction of the…The comparison of curcumin and naringenin effects on motor function in rotenone model of Parkinson’s disease
Objective: The aim of the study was to compare the effects of curcumin and naringenin on rotenone-induced motor deficits and related neurochemical changes. Background: Experimental…Quantitative investigation of the pathway between dopamine receptors and Ca2+ channels in layer II stellate cells towards Parkinson’s disease
Objective: Recent experimental data suggest a putative coupling between dopamine D2 receptors (D2R) and T-type Ca2+ channels as another biophysical explanation for the firing pattern…Tramadol Induces Neuroinflammation, Mitochondrial Oxidative Stress, Neurotransmitters Dysbalanced and Produced Parkinson’s Disease Like Symptoms in Experimental Wistar Rats
Objective: The current study is designed to evaluate the possible neurotoxic effects of tramadol in Wistar rats. Background: Parkinson’s disease (PD) is a chronic neurodegenerative…Asymmetry of striatal dopaminergic function in essential tremor is associated with kinetic tremor asymmetry
Objective: To investigate possible dopaminergic pathophysiology of essential tremor (ET) by focusing on tremor asymmetry. Background: Essential tremor (ET) is considered a non-dopaminergic movement disorder.…Effect of dietary caffeine on brain dopamine transporter binding in Parkinson’s disease
Objective: To investigate the relationship between dietary caffeine intake and striatal dopamine function over the progression of Parkinson’s disease (PD). Background: The association between high…Anodal transcranial direct current stimulation could change the metabolomic profiles of cerebrospinal fluid in Parkinson’s disease
Objective: We tried to identify meaningful metabolite change after anodal tDCS in clinically diagnosed PD patients by adopting metabolomic analysis Background: Transcranial direct current stimulation…Long duration response to levodopa in advanced Parkinson disease
Objective: In patients with advanced Parkinson disease, it is possible to obtain a response to duodopa, if the dose is adjusted appropriately, even taking periods…
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