Response inhibition in Parkinson’s disease
Objective: To study the brain networks underlying Response Inhibition in Parkinson's disease (PD). Background: While some PD patients can have significant executive dysfunction, others remain…Beta – blockers worsen vascular parkinsonism in patients with concomitant coronary heart disease
Objective: Our primary aim was to study the effect of beta - blockers on the dynamics of extrapyramidal disorders in patients suffering from coronary heart…Efficacy and safety of a L-dopa delivery and monitoring medical device
Objective: The objective of this study is to evaluate algorithms in a medical device for l-dopa delivery and monitoring. This wearable medical device will measure…Arterial spin labeling perfusion MRI compensate for other diagnostic tools in evaluation of Parkinson’s disease with dementia
Objective: To test usefulness of arterial spin labeling (ASL) perfusion MRI for diagnoses of Parkinson's disease (PD) with dementia. Background: Dopamine transporter (DAT) images may…The effect of dopamine on global versus specific inhibitory control in Parkinson’s disease
Objective: To evaluate the effect of dopaminergic medication on inhibitory control using a novel go/no-go task in Parkinson's disease (PD). Global cognition and motor examination…Reduced lifespan and climbing ability observed in the overexpressing human α-synuclein without heat shock protein CNB115 in Parkinson’s disease drosophila line
Objective: To investigate the neurotoxic role of overexpressing α-synuclein without Heat Shock Protein CNB115 (HSP115) in Parkinson's disease Drosophila line. Background: Parkinson's disease (PD) is…Prevalence of impulse control disorders among adult Filipino patients with idiopathic Parkinson’s disease seen at a tertiary center in Manila
Objective: (1) To determine the prevalence and severity of Impulse Control Disorders (ICDs) in adult Filipino patients with idiopathic Parkinson's disease seen at a tertiary…Consolidation of learning and memory in Parkinson’s disease
Objective: To determine if Parkinson's disease causes an impairment in the ability to consolidate learning into long-term memory and to determine if this deficit is…Subthalamic nucleus deep brain stimulation modulate catecholamine levels with significant relations to clinical outcome after surgery in patients with Parkinson’s disease
Objective: Because subthalamic nucleus deep brain stimulation is effective in L-3,4-dihydroxyphenylalanine responsive patients with Parkinson's disease (PD), the preoperative catecholamine levels may affect the effect…Functional characterisation and the selective vulnerability of SNCA (A30P) patient-derived midbrain dopaminergic neurons to ER stress
Objective: To functional characterise and phenotype the genetic Parkinson's disease (PD) patient with an A30P point mutation in SNCA using midbrain dopaminergic neurons (mDANs) vs…