Effect of Best Practice Advisory on the administration of contraindicated medications to hospitalized patients with Parkinson’s disease and related disorders
Objective: To determine if a best practice advisory (BPA) reduced the orders and administration of contraindicated dopamine blocking agents (DBA) to hospitalized patients with Parkinson’s…Long-term safety and durability of effect of ecopipam in pediatric patients with Tourette Syndrome: Results of a 12-month open-label extension (OLE) study
Objective: Assess the safety and durability of effect of long-term treatment with ecopipam in pediatric patients with Tourette syndrome (TS). Background: TS is a childhood-onset…Efficacy of levodopa/carbidopa/entacapone replacement of levodopa/dopa decarboxylase inhibitors in treatment of Chinese Parkinson’s disease patients with wearing-off: a multicenter, randomized controlled, open label study
Objective: This study aimed to investigate the efficacy and safety comparison between LCE and Pramexol in Chinese PD patients with the wearing-off phenomenon. Background: Wearing…A Case series of Hemichorea Hemiballism Associated with Non-ketotic Hyperglycemia and Unique Imaging findings
Objective: To avoid missed diagnosis of non-ketotic hyperglycemic hemichorea hemiballismus by discussing the phenomenology, radiological findings and therapy through this case series. Background: Hemichorea–hemiballismus associated…Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study of Ecopipam in Children and Adolescents with Tourette Syndrome
Objective: Evaluate the efficacy and safety of ecopipam in children and adolescents with Tourette’s Syndrome (TS). Background: Ecopipam, a first-in-class selective dopamine-1 (D1) receptor antagonist…Malignant catatonia secondary to clozapine withdrawal: A case report
Objective: To report a patient with malignant catatonia from abrupt clozapine discontinuation. Background: Clozapine blocks 5HT2A/5HT2C serotonin and dopamine receptors. Cholinergic and serotoninergic rebounds have…Long-term safety and activity of ecopipam (ECO), a selective D1 antagonist during treatment of pediatric patients with Tourette Syndrome
Objective: To evaluate the long-term safety and activity of ecopipam (ECO) in the treatment of children and adolescents with Tourette syndrome (TS). Background: D2 antagonists…The association between antipsychotic-induced akathisia and suicidality: a systematic review
Objective: This systematic review aims to establish whether a causal association exists between antipsychotic-induced akathisia and suicidality, in order to guide further clinical decision making…Belly dancer’s dyskinesia due to prochlorperazine
Objective: We aim to present a case report of abdominal wall dyskinesia as a tardive syndrome of prochlorperazine. Background: The clinical presentation of involuntary choreiform…Asymmetrical resting legs tremor induced by levosulpiride
Objective: Our aim is to report unusual case of woman who presented asymmetrical resting tremor of both legs induced by levosulpiride. Background: Resting tremor of…