The impact of a wearable device on Parkinson’s disease motor symptom management in patients starting rotigotine transdermal patch
Objective: Open-label, multi-center pilot study (PD0049) to evaluate the impact of Kinesia 360 (an “at home” wearable device) on motor symptom management in Parkinson’s disease…EEG microstates changes in response to increase in dopaminergic stimulation in treated typical Parkinson’s disease patients without clinical fluctuations
Objective: Neurotropic drugs may modulate Electroencephalography (EEG) microstates (MS), but there are no works showing EEG MS default-mode network changes in response to dopaminergic stimulation…Impulse control disorders and compulsive behaviours in Parkinson’s disease. Results from the COPPADIS Study Cohort
Objective: Our objective was to analyze the existence of impulse control disorders (ICDs) and compulsive behaviours (CBs) in Parkinson’s disease (PD) patients compared to control…Lottery choice task as a detect tool for PD patients with pathological gambling
Objective: We aim to develop a tool lack of stigma to detect patients' impulse control problems. Background: Dopaminergic medication is current major treatment for Parkinson's…Validation of a One-Page Impulse Control Disorder Questionnaire in a Parkinson’s Disease Clinic
Objective: We seek to report data on ICD symptoms collected on 120 patients with Parkinsonism attending specialist movement disorder outpatient clinics using a newly devised,…Rotigotine protects dopaminergic neurons by targeting serotonin 1A receptors on astrocytes
Objective: In this study, we examined neuroprotective effects of rotigotine and involvement of serotonin 1A (5-HT1A) receptors on astrocytes in neuroprotective action of the drug…Dissociate effect of dopaminergic therapy in reward expectation and prediction error in PD patients with comorbid impulse control disorder
Objective: To study EEG oscillatory activity associated to reward prediction error in Parkinson’s disease (PD) patients with impulse control disorders (ICD) and determine how dopaminergic…Emulating the natural timing of dopamine receptor activation in Parkinson’s Disease
Objective: To emulate physiological dopamine receptor activation, in order to restore temporal patterns of dopamine-like signalling and normalise function in the striatum in Parkinson's disease.…GASTROPARK: Multicenter study on the efficacy of dopamine agonists for gastrointestinal symptoms in Parkinson’s disease
Objective: Main: To assess the modification of gastrointestinal symptoms in patients with Parkinson's disease before and after the introduction of dopamine agonists. Secondary: (1) To…Effectiveness of Rotigotine plus Intensive and Goal-based Rehabilitation versus Rotigotine alone in “de-novo” Parkinsonian subjects: A Randomized Controlled Trial with 18-month Follow-up
Objective: To evaluate the synergism between Dopamine Replacement Therapy (DRT) and rehabilitation in treating Parkinson's disease (PD), by investigating the short and the long-term effectiveness…
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