Changes in Inhibitory Control Differentiate Progressive Supranuclear Palsy from Early Parkinson’s Disease
Objective: To describe distinct type of errors and frequency of perseverative errors in executive, memory, language, and attentional tasks in PSP and PD. Background: Progressive…Yawning Associated Parakinesia Brachialis Oscitans, Penile Erection, and Truncal Seizures Following Intracerebral Hemorrhage
Objective: To describe a rare case of parakinesia brachialis oscitans (PBO) with yawning-associated penile erection and truncal seizures in a patient with a right middle…Exploring Visual Scanning Behavior and Novelty Seeking in Parkinson’s Disease: A Pilot Study
Objective: To assess the feasibility of eye-tracking metrics in a Visual Paired Comparison (VPC) task as biomarkers for impulsivity in Parkinson's disease (PD) and to…Noradrenaline treatment of apathy and impulsivity in participants with Progressive Supranuclear Palsy syndromes (NORAPS). A Phase II clinical trial – ISRCTN99462035.
Objective: The NORAPS Phase II clinical trial seeks to demonstrate safety, tolerability and efficacy of atomoxetine in Progressive Supranuclear Palsy (PSP). Background: PSP is a…EFFECTS OF DOPAMINERGIC MEDICATION ON REACTIVE AND PROACTIVE INHIBITORY CONTROL
Objective: In this study, we aim to address the effects of dopaminergic treatment (DT) on the two domains of motor inhibition [1], i.e., reactive (the…Dopamine-independent cortical disinhibition in Parkinson’s disease
Objective: To test the hypothesis that cortical disinhibition in Parkinson's disease is a dopamine-independent process. Background: Motor cortex alterations in Parkinson's disease are classically considered…High- and Low-Frequency Deep Brain Stimulation in the Subthalamic Nucleus differentially modulate Response Inhibition and Action Selection in Parkinson’s Disease
Objective: The aim of this project was to investigate how high- and low-frequency deep brain stimulation (DBS) modulate impulsive actions in the antisaccade task as…Effect of oxytocin on response inhibition in Parkinson´s disease: a pilot study
Objective: To observe the effect of oxytocin (OXT) on response inhibition in Parkinson´s disease (PD) patients using dedicated saccadic tasks. Background: Cumulating evidence has shown…The volume of STN tissue activated by DBS and the strength of its structural connectivity with SMA predicts the effects of STN-DBS on response inhibition
Objective: To test the hypothesis that antidromic activation of the hyperdirect pathway might mediate the effects of STN-DBS on movement initiation control. Background: In PD,…Decreased mesencephalic locomotor region activation explains loss of presynaptic inhibition during step initiation in people with Parkinson´s disease with freezing of gait
Objective: To investigate if decreased mesencephalic locomotor activation (MRL) activation during step initiation in an-event related fMRI protocol would explain the loss of presynaptic inhibition…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.