Beyond Medication: The Potential of Diet in Parkinson’s Management
Objective: To assess the effects of diet and dietary supplements on motor/non-motor symptoms, and disease progression in Parkinson disease (PD). Background: Diet has generally played…A multi-center, randomized, controlled study of the add-on effect of selegiline or zonisamide to L-dopa/DCI therapy in Parkinson’s disease (DATSZ-PD study)
Objective: To investigate the efficacy and safety for neuroprotection and disease modifying effect in selegiline(SL) or zonisamide(ZN) by using UPDRS, PDQ-39 and DAT -SPECT in…A Novel Therapeutic Targeting the tPA-NMDAr Interaction for Parkinson’s Disease
Objective: Glunomab, a monoclonal antibody designed to inhibit the interaction between tissue plasminogen activator (tPA) and the N-methyl-D-aspartate receptor (NMDAr), has demonstrated therapeutic potential across…Prodromal Parkinson’s Disease in Agent Orange Exposed US Vietnam Veterans
Objective: 1-Comparing the risk of prodromal PD between AO exposed veterans (AOEV) and non-AO exposed veterans without PD (Controls) in a Veterans Affairs (VA) hospital…VGN-R09b, an Adeno-associated virus-based Combination Gene Replacement Therapy for Parkinson’s Disease
Objective: Develop a sustained disease modifying gene therapy for treating Parkinson’s disease Background: Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons…Educational Strategies for Enhancing Caregiver Knowledge and Capacities in Parkinson’s Disease Management: A Comprehensive Review
Objective: To evaluate the effectiveness of educational strategies in enhancing caregiver knowledge, skills, and confidence in managing Parkinson’s disease (PD) and to identify gaps in…An Exercise Prescription to Slow the Progression of Parkinson’s Disease
Objective: To evaluate the efficacy of a 12-month, home-based, high-intensity aerobic exercise intervention in slowing the progression of Parkinson’s disease (PD) using rate-focused cycling. Background:…Apathy and Risk of Parkinson’s Disease: A Population-Based Cohort Study
Objective: This study investigated the association between apathy and the risk of incident Parkinson's disease (PD) in community-dwelling adults. Background: Apathy is a core neuropsychiatric…Effect of Exenatide on disease progression in early Parkinson’s disease–a randomized, placebo controlled, single-center trial in Sweden
Objective: To identify biological mechanisms that mediate Exenatide's effect in the brain of patients with early Parkinson’s disease(PD). Background: Tracking PD progression remains a major challenge due to…The Bjorn Moller Research Repository: A Resource for Movement Disorders Research
Objective: To build a repository of longitudinally collected biological samples and clinical, demographic, and lifestyle data from individuals with Parkinson’s disease (PD) and other movement…
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