Cognitive function and self-reported depressive symptoms in a population-based cohort to study non-motor-symptoms of Parkinson’s disease
Objective: To describe the relation of depressive symptoms with cognitive performance in our cohort at baseline and two-year follow-up. Background: Cognitive function (CF) is frequent…Neuroprotective and antidepressant-like effects of the endogenous amines from tetrahydroisoquinoline group TIQ and 1MeTIQ in the animal model of depressive disorder: Behavioral and neurochemical studies in the rat
Objective: For the purpose of estimation neuroprotective and antidepressant-like effects of the endogenous amines 1,2,3,4-tetrahydroisoquinoline (TIQ) and its close methyl derivative, 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) in the…Relationship between the MDS-UPDRS and quality of life in Parkinson’s disease: A large international multicenter study of 3206 patients (the QUALPD study)
Objective: To evaluate the relationship between the International Parkinson and Movement Disorder Society – Unified Parkinson's disease Rating Scale (MDS-UPDRS) and Quality of Life (QoL)…The role of depression in suicidal ideation in a sample of patients with Parkinson’s disease
Objective: The objective of this study was to assess the frequency of suicidal ideation and suicide attempts in a sample of consecutive patients with Parkinson's…Preclinical evaluation of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias: Is it a ‘chemical’ DBS?
Objective: To evaluate mechanism of long-term activity of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias (LID). Background: Ketamine is an anesthetic that, when administered as…Greater incidence of depressive symptoms in atypical parkinsonism: Importance of early screening
Objective: To evaluate the incidence of depressive symptoms in Parkinsonian patients in a large cohort followed at a tertiary movement disorders center. Background: Despite relative…Life satisfaction in Parkinson’s disease – associated factors
Objective: To identify factors associated with life satisfaction (LS) in people with Parkinson's disease (PD), including a specific focus on those with late stage PD.…Relation between personality trait and depression in Parkinson’s disease
Objective: 1. To investigate personality trait of patients with Parkinson's disease (PD). 2. To clarify the relationship between personality trait and depression in patients with…Patient case reports supporting a long-term effect of sub-anesthetic ketamine infusion in reducing L-DOPA-induced dyskinesias
Objective: To evaluate possible long-term anti-dyskinetic activity of low-dose sub-anesthetic ketamine infusion from a retrospective chart review. Background: Repurposing drugs that have already been proven…
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