Clinical, Neurophysiological, and Biological Insights into Levodopa-Induced Dyskinesias
Objective: The aim of this study was to determine the clinical, neurophysiological and biological features of Parkinson's Disease (PD) patients with L-Dopa-induced dyskinesias (LIDs). Background:…Synaptic density and α-synuclein oligomers in skin biopsies: differences between idiopathic and GBA-linked Parkinson’s disease
Objective: To compare α-synuclein oligomers and synaptic density (SD) in skin biopsies from PD and GBA-PD. Background: Previous research [1] reported α-synuclein oligomers within synaptic terminals of autonomic fibers in…A case of idiopathic lower limb dystonia treated with combined use of botulinum toxin type A and phenol nerve block
Objective: Here we report a case of focal LLD successfully treated with combined botulinum neurotoxin type A (BoNTA) and Nerve block (NB). Background: Among focal dystonias,…Ultrasound-guided selective diagnostic nerve block in patients with elbow spasticity: a retrospective pilot study.
Objective: To evaluate efficacy and patients’ perception of the ultrasound-guided selective diagnostic nerve block (DNB) of the motor branch for brachialis muscle compared with the…Comparison of Disease Progression in Patients with Brain-first versus Body-first Parkinson’s Disease
Objective: This study aimed to compare the clinical progression between brain-first and body-first PD groups using cardiac sympathetic denervation (CSD). Background: Brain-first and body-first Parkinson’s…Limb myorhythmia treated with chemodenervation: A case report
Objective: To describe the case of a patient with limb myorhythmia successfully treated with bolutinum toxin injections. Background: Myorhythmia is a rare condition characterized by…Does autosomal recessive Parkinson’s Disease behave as “Brain-first” subtype?
Objective: The aim of this study is to explore whether monogenic PD (due to parkin or DJ-1 homozygous mutations) can be subtyped as "brain-first" by…Fundamental changes in Nerve Conduction Velocity and hyperpolarization latency of action potential of Sciatic nerve at the pre-motor phase in a chronic PD in vivo model: a neurotool for Parkinson’s disease diagnosis
Objective: To evaluate the changes in NCV and hyperpolarization latency of action potential of Sciatic nerve at the pre-motor phase in MPTP induced chronic PD…Lateralization of cochlear dysfunction as a specific biomarker of Parkinson’s disease; role for cholinergic transmission?
Objective: To understand to what extent an early cochlear dysfunction may represent an additional non-motor signature of Parkinson’s disease (PD) patients. Further, whether it may…FUNCTIONAL MOTOR SYMPTOMS IN PARKINSON’S DISEASE, AND FUNCTIONAL PARKINSONISM: A SYSTEMATIC REVIEW
Objective: This following review aims to clarify the link between functional and organic parkinsonism, in order to improve the understanding of functional symptoms in PD.…