Extent of cognitive impairment in Parkinson`s disease with Covid-19
Objective: To study of the extent of cognitive impairment in PD patients with Covid-19. Background: Covid-19 may aggravate the clinical course of Parkinson's disease (PD)…Effect of Sex on the association between GBA mutations and Cognitive Decline in Parkinson’s Disease
Objective: To assess the impact of sex and glucocerebrosidase (GBA) mutations on cognitive trajectories in a sample of Parkinson's disease (PD) patients. Background: Accumulating evidence…Amyloid status differentiates synaptic loss and atrophy in Corticobasal Syndrome.
Objective: In this observational/cross-sectional study, we tested whether the degree and extent of in vivo synaptic loss differed in patients with corticobasal syndrome according to…Cholinergic deficits in Parkinson Disease
Objective: To determine whether loss of cholinergic projections to cortical and limbic regions contributes to the development of dementia in Parkinson’s disease (PD). Background: PD…Atypical parkinsonism and psychiatric disorder in hereditary diffuse leukoencephalopathy with spheroids: a novel variant in the CSF1R gene
Objective: We describe the clinical, radiological and neuropathological phenotype of a patient carrying a novel variant in the CSF1R gene. Background: Hereditary diffuse leukoencephalopathy with…Exploring brain mechanisms of identity attribution in presence hallucinations of Parkinsonian origin
Objective: Study cognitive, behavioral correlates of identity of presence hallucinations in Parkinson’s disease. Background: Presence hallucination (PH), the sensation that someone is nearby when no…Long-term dementia prevalence in Parkinson disease: Glass half-full?
Objective: To determine long-term, cumulative dementia prevalence rates in Parkinson disease (PD) using data from two large, ongoing, prospective observational studies. Background: Dementia is reported to occur in…Mitochondrial DNA copy number is associated with the severity of motor symptoms and dementia in Parkinson’s disease
Objective: We aimed to investigate the diagnostic and prognostic role of blood mitochondrial DNA copy number (mtDNA-CN) measured by whole genome sequencing (WGS) in relation…Oculomotor parameters measured during free viewing of video differentiate Parkinson’s disease from progressive supranuclear palsy
Objective: Characterize oculomotor phenotypes comprised of saccade, pupil, and blink behaviour for progressive supranuclear palsy (PSP) and Parkinson’s disease (PD) with differing degrees of cognitive…Is an integrated Parkinson’s Dementia Service the way forward?
Objective: To illustrate the role of a single team in managing all facets of Parkinson’s Background: The Cardiff and Vale Parkinson’s service is an integrated,…
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