Synaptic function in Parkinson’s disease associated with GBA mutations
Objective: To investigate the pathological substrate of impaired cognition in Parkinson’s disease (PD) associated with glucocerebrosidase (GBA) mutation. Background: Mutations in glucocerebrosidase gene (GBA), originally…Visual hallucinations in Parkinson´s disease and amyloid burden: 18F-Flutemetamol PET-MRI study
Objective: To compare amyloid distribution in patients with Parkinson´s disease (PD) with visual hallucinations (VH-p) and without (VH-n). Background: In patients with PD the prevalence…Comparison of Zonisamide with Non-Levodopa, Anti-Parkinson’s disease Drugs in the Incidence of Parkinson’s Disease-Relevant Symptoms
Objective: This study was to compare zonisamide and other anti-PD drugs by analyzing their associations with the incidence of PD-relevant symptoms. Background: Patients with Parkinson’s…Case-control study of risk developing parkinsonism in Alzheimer’s disease in relation to hypertension, dyslipidemia, and diabetes in Taiwan
Objective: To clarify the relationship between vascular risk factors and parkinsonism in Alzheimer’s disease Background: This case-control study investigated the associations of a history of…Severe hypomimia in drug naïve Parkinson´s disease patients may predict mild cognitive impairment
Objective: We aimed to analyze if hypomimia was associated with mild cognitive impairment in Parkinson´s disease (PD-MCI) and if it predicted cognitive decline. Background: Hypomimia…Cognitive impairment in patients with Parkinson’s Disease
Objective: The objective is to study the relation between cognitive impairment with the form and stage of PD. Background: Currently, there is a tendency of…Clinical Response to 72-h Lumbar CSF Drainage in Idiopathic Normal Pressure Hydrocephalus associated with Parkinsonism: Timing and Correlates
Objective: To evaluate timing and clinical correlates of motor response after 72-h lumbar CSF drainage in patients with Normal Pressure Hydrocephalus (iNPH) associated with parkinsonism.…Self-report of cognitive functional abilities is inaccurate in PD-MCI and PDD
Objective: Evaluate concordance between self-reported and performance-based measures of cognitive functional abilities in PD by cognitive class. Background: PD-specific cognitive functional questionnaires, the Penn Daily…Neuroanatomical correlates of early cognitive change in Parkinson’s disease
Objective: To identify the neuroanatomical basis of early cognitive change in Parkinson’s disease (PD). Background: 50% of PD patients develop dementia within 10 years of…Parkinson Disease Clinical Subtypes Predict Dementia and Mortality Risk
Objective: To identify PD clinical subtypes based on patterns of motor, cognitive, and psychiatric symptoms; to assess the clinical utility of each subtype in predicting…
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