CHARACTERIZATION OF LRP10 EXPRESSION IN LEWY BODY DISORDERS AND IPSC-DERIVED BRAIN CELLS
Objective: Our objective is to characterize endogenous low-density lipoprotein-related protein 10 (LRP10) expression in human induced pluripotent stem cell (iPSC)-derived brain cell types, post-mortem brain…Differentiation of Mild Cognitive Impairment (MCI) progression to Alzheimer Disease (AD) vs Dementia with Lewy Bodies (DLB): Is this possible neuropsychologically?
Objective: Aim of the present review study was to describe and compare the neurocognitive features of MCI which could predict its progression to DLB vs…Evaluation of bedside tests of attention in delirium superimposed on Parkinson’s disease and dementia
Objective: To evaluate the ability of simple bedside tests for attention to detect delirium in those with and without underlying neurodegenerative diseases, including Parkinson’s disease…Early-onset Dementia with Lewy Bodies and Parkinson’s Disease Dementia: A Population-based Study (2010-2015).
Objective: To examine the incidence, clinical features, and survival of early-onset Dementia with Lewy Bodies and Parkinson’s Disease Dementia (DLB/PDD) (≤55 years of age) in…Utilizing digital biomarkers to explore risk factors for falls in patients with Lewy Body Dementia
Objective: To analyze risk factors for falls in individuals with Lewy Body Dementia (LBD) enrolled in PRESENCE. Background: PRESENCE was a phase 2 clinical trial…Differential methylation signatures in Lewy body dementia
Objective: This study aimed to compare the DNA methylome of Lewy body dementia (LBD) patients and healthy controls. Background: LBD is the second most common…Evaluating the use of digital biomarkers to test treatment effects on cognition and motor in patients with Lewy Body Dementia
Objective: To evaluate if frequent cognitive and motor tests using an iPad app and a wrist-worn actigraphy watch to track activity and sleep can detect…Can event-related oscillations aid in differentiating Parkinson’s disease and dementia with Lewy bodies?
Objective: To assess the specificity of an EEG signature of the visual event-related oscillations (ERO) in synucleinopathies. Background: Parkinson's disease (PD), PD dementia (PDD) and…Relationship Between a-syn RT-QuIC and a-syn Neuropathologic Burden in Dementia with Lewy Bodies
Objective: To determine if measures of alpha-synuclein (a-syn) real time quaking induced conversion (RT-QuIC) activity are related to a-syn neuropathologic burden in dementia with Lewy…Confrontation Naming Deficit in Lewy Body Dementia Patients with Alzheimer’s Disease Co-Pathology
Objective: To test the association between confrontation naming performance and Alzheimer’s disease (AD) co-pathology as defined by cerebrospinal fluid (CSF) biomarkers in Lewy body dementia…
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