Visualising cholinergic nerves in dementia with Lewy bodies using PET and FEOBV
Objective: Investigate the cholinergic integrity of the central nervous system in dementia with Lewy bodies using PET and a tracer for the vesicular acetylcholine transporter.…Learning to PERSEVERE: Efficacy and Feasibility of Peer Mentor Support and Caregiver Education in Lewy Body Dementia
Objective: To examine the effects of peer mentoring on caregiving mastery, Lewy Body Dementia (LBD) knowledge, and dementia attitudes among LBD family caregivers. Background: Few…Connectivity of dopaminergic networks in the continuum of Dementia with Lewy Bodies
Objective: To examine local and long-distance dopaminergic changes in prodromal DLB (pDLB) patients in a comparison with matched controls and overt DLB dementia patients. Background:…Drivers of burden over time in caregivers of patients with Parkinson’s disease and related disorders: Findings from a community-based clinical trial of outpatient palliative care
Objective: To identify predictors of accelerated caregiver burden in patient-caregiver dyads of people with Parkinson’s disease and related disorders (PDRD). Background: PDRD are characterized by…Sex Modulates Cognitive Association of Lewy Body Pathology
Objective: To assess whether the association between Lewy body (LB) pathology stages and cognition differs for women and men Background: Progression of LB pathology is…Illusory responses across the Lewy body disease spectrum
Objective: To study pareidolias in patients across the Lewy body disease-spectrum, including those without psychosis. Background: Pareidolias are specific illusions of faces and objects perceived…Investigating genetic risk factors for Lewy body dementia
Objective: We aim to investigate the genetic mutations related to the development of dementia in Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB)…FDG-PET features of Lewy body dementia among patients with amnestic presentations typical for Alzheimer’s disease
Objective: To better understand the role of FDG-PET for identifying dementia with Lewy bodies (DLB) in the context of Alzheimer’s disease (AD)-like amnestic presentations, we…Safety, Target Engagement and Effects of Bosutinib in Dementia with Lewy Bodies
Objective: To investigate the safety, biomarkers effects and determine the lowest effective dose of Bosutinibin Dementia with Lewy Bodies (DLB) Background: The effects of bosutinib,…Effects of white matter hyperintensities, neuropsychiatric symptoms, and cognition on activities of daily living: Differences between Dementia with Lewy Bodies and Alzheimer’s disease
Objective: To investigate if White matter hyperintensities (WMHs), neuropsychiatric symptoms and cognitive performance associate with, and/or predict activities of daily living (ADLs) differently in Alzheimer’s…
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