Keeping patients out of care facilities— clozapine rescues Parkinson’s patients with troublesome psychosis unresponsive to quetiapine and pimavanserin.
Objective: We describe a single-center cohort of Parkinson patients in crisis with troublesome psychosis unresponsive to quetiapine and pimavanserin, who were rescued by treatment with…Combined GWAS of Dementia with Lewy Bodies, REM-Sleep Behavior Disorder, Parkinson’s Disease and Alzheimer’s Disease
Objective: To identify genetic variants that are either shared between or specific for Dementia with Lewy Bodies (DLB), REM Behavior Disorder (RBD), Parkinson’s disease (PD)…Utility of quantitative EEG during sleep as a potential biomarker of Lewy body disease progression
Objective: Objective: To assess whether progression from isolated REM sleep behaviour disorder (iRBD), established Parkinson’s disease (PD) and Dementia with Lewy bodies (DLB) are accompanied…Are patients presenting earlier in time? Secular changes in REM sleep behavior disorder
Objective: To determine if secular changes occur in REM sleep behavior disorder (RBD). Background: RBD is the strongest clinical marker of prodromal synucleinopathy, and provides…Myocardial sympathetic denervation biomarkers for early detection of prodromal DLB
Objective: Because of the time course of detecting DLB symptoms and signs, DLB is poorly diagnosed and hardly differentiate from AD, especially in early stage…Potentially inappropriate medication useage among patients newly diagnosed with dementia with Lewy bodies
Objective: Investigate the use of potentially inappropriate medications (PIM) among patients newly diagnosed with dementia with Lewy bodies (DLB). Background: PIM, including anticholinergics, are associated…Prodromal dementia with Lewy bodies in REM sleep behavior disorder: A multicenter study
Objective: To assess the progression and predictive value of neuropsychological testing on the development of dementia in idiopathic REM sleep behavior disorder (iRBD). Background: iRBD…Sleep seasonality in alpha-synucleinopathies: a comparative study with non-neurological sleep disorder patients
Objective: To assess month of the year related changes in polysomnography (PSG) data in patients with alpha-synucleinopathies. Background: Season of the year related changes in…Longitudinal free-water changes in dementia with Lewy bodies
Objective: To characterize longitudinal diffusion microstructural changes in individuals with dementia with Lewy bodies (DLB). Background: Diffusion-weighted MRI (dMRI) examines tissue microstructure integrity in vivo.…T1 MRI reveals differential hippocampal atrophy in Lewy body disorders with and without Alzheimer’s copathology
Objective: Determine whether MRI can identify differences in hippocampal volume between patients with Lewy body disorders with and without Alzheimer's copathology, and whether these differences…
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