Compensatory Dynamic Brain Network Mechanisms in Early Lewy Body Dementia: An rs-fMRI Study
Objective: To investigate compensatory dynamic brain network mechanisms in early Lewy body dementia (LBD), specifically mild cognitive impairment with Lewy bodies (MCI-LB), using resting-state functional…Multiplex Proteomic Analysis of Lewy Body Dementia Reveals Cerebrospinal Fluid Biomarkers of Disease Pathophysiology and Progression
Objective: To evaluate the performance of a multiplexed proteomic assay in a large multi-center Lewy Body dementia (LBD) cohort. Background: LBD, which comprises Parkinson’s disease…Medication Administration Burden in Lewy Body Dementia Caregivers
Objective: To evaluate medication administration burden among Lewy Body Dementia (LBD) family caregivers and associations with caregiver and care recipient characteristics. Background: Family caregivers of…Sleep Quality among Lewy Body Dementia Family Caregivers
Objective: To explore the relationship between caregiver sleep quality and caregiver and care recipient characteristics in Lewy Body Dementia (LBD). Background: LBD family caregivers have…Acceptability, Feasibility, and Appropriateness of wearable technology in Lewy body dementia
Objective: Determine implementation outcomes of Apple watches amongst individuals with Lewy body dementia (LBD) and their care partners. Background: Wearable technology can provide valuable information about…Anti-Diabetic Medications to Fight Parkinson’s Disease and Lewy Body Dementia
Objective: To evaluate the tolerability and clinical effects of newer antidiabetic drugs in individuals with Parkinson's disease (PD) and Lewy body dementia (LBD). Background: Parkinson’s…Elevated Risk of Dementia with Lewy Bodies subsequent to Military Trauma
Objective: Evaluate the association between traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) among US Veterans with subsequent development of Dementia with Lewy Bodies…Multipronged, Community-Engaged Approach to Recruiting Lewy Body Dementia Family Caregivers for a National Trial
Objective: Describe a three-tiered initiative to recruit Lewy Body Dementia (LBD) family caregivers into a national randomized controlled trial (PERSEVERE, NCT06389032). Background: LBD is often…The Syn-D Study: Detection of Cutaneous Phosphorylated Alpha-Synuclein and blood P-Tau 217 in Patients with Mild Cognitive Impairment
Objective: To quantify the deposition of cutaneous P-SYN and blood P-Tau 217 in patients with suspected DLB and AD at the mild cognitive impairment (MCI)…Plasma Biomarkers Predict Clinical Outcomes in Individuals with Neuronal α-Synuclein Disease and Amyloid-β Co-Pathology
Objective: We examined whether the plasma biomarkers pTau181, pTau217, GFAP, NfL, and Aβ42/40 are associated with cognitive, functional, and motor outcomes in individuals with neuronal…
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