Angiotensin-converting enzyme inhibitors are neuroprotective regarding APOE-mediated motor and non-motor experiences for Alzheimer’s dementia but not for dementia with Lewy bodies
Objective: To assess whether angiotensin-converting enzyme (ACE) inhibitors modulate associations of biofluid concentrations and activity of ACE with motor and non-motor experiences in dementia with…Dual task walking differentially affects toe clearance in Lewy body disease: A contributor to dynamic falls risk?
Objective: To evaluate the change in gait and minimum toe clearance when walking under dual task in different dementia sub-types as a contributor to dynamic…Efficacy and safety of Rasagiline in treatment of gait disturbances in dementia with Lewy bodies
Objective: We aimed to investigate the efficacy and safety of rasagiline in addition to levodopa in patients with dementia with Lewy bodies (DLB). Background: Management…Insulin degrading enzyme, a novel key protein against alpha-synuclein oligomers formation?
Objective: The objective of this work is to study the interaction between α-synuclein and the insulin degrading enzyme in the pancreas of subjects with synucleinopathies.…Improved diagnosis of dementia with Lewy bodies by the combination of Tc-99m ECD SPECT with eZIS analysis and quantitative TRODAT-1 SPECT images
Objective: The development of easily useful neuroimaging may resolve to the delays of diagnosis. Background: Dementia with Lewy bodies (DLB) is easy to be misdiagnosed…Voxel-based Analysis of Cholinesterase Inhibitor Response in Lewy Body Disorders: A Prospective Observational Study
Objective: The objective is to investigate functional neuroimaging correlates of response to ChEIs in LBD. Background: Lewy body disorders (LBD), including dementia with Lewy bodies…Defective visual perception in patients with Lewy body disease: assessment of hallucinations with pareidolia test.
Objective: Hallucination is a common feature in patients with advanced Parkinson’s disease(PD) and dementia with Lewy bodies (DLB). Background: The pareidolia test is a tool…Feasibility, tolerability and acceptance of a psychosocial intervention for people with Parkinsonian dementia: The INVEST trial.
Objective: To compare a companion-guided, home-delivered psychosocial stimulation intervention to treatment as usual (TAU) to inform a large-scale efficacy trial for people with cognitive impairment…A new psychosocial intervention for people with Parkinsonian dementias: Adherence, barriers and facilitators
Objective: To investigate participant adherence and engagement to a home-based, companion-guided cognitive stimulation therapy adapted for people with Parkinsonian dementias (CST-PD). Background: Adherence to rehabilitation…Do Acetylcholinesterase Inhibitors (AChEI) delay institutionalisation in Parkinson’s and Lewy Body Disease?
Objective: We explored the use of Rivastigmine in Parkinson’s and Lewy body dementia through assessment of quantitative data obtained from a clinical database. We focussed…
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