Polysomnographic data in Dementia with Lewy Bodies: Correlation with clinical features and comparison with other alfa-synucleinopathies
Objective: 1) Polysomnography (PSG) assessment of sleep in Dementia with Lewy Bodies (DLB). 2) Correlation between PSG data, fluctuations and hypersomnolence. 3) Comparison of PSG…Interaction of TDP-43 with IAPP in pancreatic beta cells of patients with sinucleinopathies
Objective: We have investigated whether deposits of phosphorylated TDP-43 might be present in pancreatic tissue of patients with synucleinopathies. Background: The TAR DNA binding protein…Effect of Viewpoint and Visual Texture on Object Recognition in Dementia with Lewy Bodies and in Alzheimer’s Disease
Objective: To examine the effect of viewpoint and visual texture on visual object recognition in mild cognitive impairment (MCI) or dementia due to DLB or…Motor and non-motor correlates of APOE-ε4 mediated cerebrospinal fluid concentrations of biomarkers of amyloidogenesis and neurodegeneration in dementia with Lewy bodies compared with Alzheimer’s dementia and healthy controls
Objective: To study associations of cerebrospinal fluid biomarkers of amyloidogenesis and neurodegeneration with motor and non-motor aspects of daily experiences in dementia with Lewy bodies…Papez circuit atrophy in Dementia with Lewy Bodies
Objective: In this ex-vivo study, we aimed to assess atrophy in regions and subregions of the Papez Circuit, a network important for memory function, in…Characterization of color vision impairment in Lewy Body Diseases
Objective: We sought to characterize the prevalence of color vision impairment in DLB patients and investigate how color vision impairment in DLB patients was associated…Comparison of Volumetric MRI measurements between Dementia with Lewy bodies and prodromal Lewy body disease
Objective: To compare the volumetric changes between patients at prodromal stage of Lewy body disese and individuals with dementia with Lewy Bodies. Background: Volumetric magnetic…The shared risk of apolipoprotein E ɛ4-allele on hippocampal volume across the spectrum of Alzheimer’s disease and dementia with Lewy bodies: Evidence from the Sunnybrook Dementia Study
Objective: To identify the association of apolipoprotein E ɛ4-allele (APOE-ε4) with hippocampal volumes across the spectrum of Alzheimer’s disease (AD) and dementia with Lewy bodies…Prevalence of REM Sleep Behavior Disorder in Sun City, Arizona
Objective: Determine prevalence of REM Sleep Behavior Disorder (RBD) in Sun City, Arizona Background: RBD is the strongest known clinical risk factor for neurodegenerative disorders…Predicting Alpha-Synuclein Pathology by REM Sleep Behavior Disorder Diagnosis
Objective: Determine sensitivity, specificity and predictive value of clinician diagnosed probable REM sleep behavior disorder (PRBD) in predicting alpha-synuclein pathology. Background: Inability to accurately diagnose…
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