Effect of Subthalamic Deep Brain Stimulation (DBS) on Impulsive Control Disorders (ICD) and Dopamine Dysregulation Syndrome (DDS) – A Randomized Controlled Trial Evaluating Deep Brain Stimulation Using a New Multiple Source, Constant-Current Rechargeable System for Management of Symptoms of Parkinson’s Disease (INTREPID)
Objective: To evaluate impulse control in participating subjects of the INTREPID randomized controlled trial (RCT). Background: Parkinson’s disease (PD) patients undergoing treatment with either medications…Directional versus omnidirectional Deep Brain Stimulation for Parkinson’s disease: Results of a prospective, blinded, multi‑center, single-arm crossover study
Objective: To evaluate the efficacy of directional Deep Brain Stimulation (DBS) by assessing the therapeutic window for directional versus omnidirectional stimulation. Background: Directional leads for…Pre-Dopa DBS: is early deep brain stimulation able to modify the natural course of Parkinson’s disease?
Objective: We review the state-of-the-art for deep brain stimulation (DBS) in Parkinson’s disease (PD) management, and present a case-series to evaluate the potential of DBS…STN-DBS programing for dyskinesia: a case report
Objective: To investigate the effect of STN stimulation on different types of dyskinesia and programming strategy. Background: Long-term use of levodopa or dopamine agonists often…High-Beta and High-Gamma Power Oscillations from Subthalamic Nucleus distinguishes Parkinson’s Disease Subtypes
Objective: To distinguish Parkinson’s disease (PD) subtypes – tremor dominant (TD) and Akinetic-rigid (AR) – by means of local field potentials spectral features recorded from…Combined Botulinum Toxin and Gpi DBS therapy in intractable cervical dystonia
Objective: To test whether the reintroduction of Botulinum Toxin Injections (BTI) after Globus pallidus interna Deep Brain Stimulation (Gpi-DBS) for intractable cervical dystonia synergistically improves…Is VIM-DBS in ET-plus patients as effective as in ET patients?
Objective: To compare the effect of deep brain stimulation (DBS) of the ventral intermediate nucleus (VIM) in patients with Essential Tremor (ET) and ET-plus (ET-p).…The concept of a ‘long lesion’ in thalamic/Zona inserta DBS for MS tremor suppression
Objective: To look at whether DBS programming to create a long field of stimulation in the thalamus-zona inserta (ZI) area is more effective, than traditional…Does the magnitude of improvement of UPDRS III at the preoperative L-dopa test predict the degree of medication decrease one year after subthalamic nucleus Deep Brain Stimulation?
Objective: To investigate whether the magnitude of improvement in motor scores of the Unified Parkinson´s Disease Rating Scale (UPDRS III) at the preoperative L-dopa challenge…“Dual Frequency” Deep Brain Stimulation Paradigm for Axial Symptoms in Parkinson’s Disease
Objective: To report the outcome of a DBS paradigm aimed at reducing axial symptoms after prolonged STN DBS. Background: High frequency stimulation (HFS) is more effective…
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