Real-world Evidence of Directional DBS Programming in Parkinson’s disease and Essential Tremor: The Cleveland Clinic Experience
Objective: Retrospective assessment of directionality in PD (STN-DBS) and ET (Vim-DBS) patients programmed in routine clinical care at the Cleveland Clinic. Background: Clinical evidence for…Modulation of Basal Ganglia and Internal Capsule Fiber Tracts During Deep Brain Stimulation for Tourette Syndrome
Objective: Our objective is to identify the fiber tracts modulated during deep brain stimulation (DBS) of the globus pallidus internus (GPi) and identify those associated…Tardive Dystonia Successfully treated with DBS
Objective: To demonstrate a successful treatment of neuroleptic-induced generalized dystonia with DBS Background: Male patient, 30 years old. At thirteen years of age, was diagnosed…Increased attention for food stimuli as a mechanism for weight gain in patients with Parkinson’s disease undergoing DBS of the subthalamic nucleus
Objective: The purpose of this study was to investigate effects of STN DBS on food cue viewing and neural processing of food stimuli in PD…A retrospective analysis of multicenter brain signal data recorded in Parkinson’s subjects implanted with deep brain stimulation leads
Objective: To assess the prevalence and factors of detectable local field potential (LFP) signals in the subthalamic nucleus (STN) of Parkinson’s disease (PD) patients. Background:…Management of parkinsonian patients with long-term DBS and incomplete control of symptoms
Objective: We want to evaluate if apomorphine infusions can improve symptom control in PD patients with long standing DBS and functional decline. Background: Deep brain stimulation…Bilateral GPi DBS for the treatment of severe generalized genetic dystonia caused by KMT2B mutation (DYT-28)
Objective: . Background: KMT2B-related dystonia (DYT-28) is a complex childhood-onset movement disorder, characterized by a limb onset dystonia progressing to generalized dystonia with cranio-cervical involvement…Case series of unilateral subthalamotomy through implanted deep electrodes: rescue therapy in Parkinson’s disease patients submitted to deep brain stimulation surgery
Objective: Evaluate clinical benefit and safety of unilateral rescue subthalamotomy, concerning motor symptoms in Parkinson’s disease (PD) patients, with partial or total deep brain stimulation…Directional versus conventional subthalamic deep brain stimulation for advanced Parkinson’s disease: Short-term outcomes of a pilot study
Objective: To investigate efficacy of STN-DBS via segmented directional leads compared to conventional omnidirectional leads in PD-patients. Background: Recently, novel leads which allow stimulation steering in…Intraoperative test objectively for discovering optimal electrode site for effective imaging (by eye) and bilateral STN-DBS stereotactic functional neurosurgery
Objective: To convolve the subject-specific (SS) electric-stimulus-field (ESF) with tremor-progress and progression quantified through accelerometer and stimulus-induced adverse side-effects (SIASE), exhibit visually (by eye) in…
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