Bilateral GPi DBS for the treatment of severe generalized genetic dystonia caused by KMT2B mutation (DYT-28)
Objective: . Background: KMT2B-related dystonia (DYT-28) is a complex childhood-onset movement disorder, characterized by a limb onset dystonia progressing to generalized dystonia with cranio-cervical involvement…Case series of unilateral subthalamotomy through implanted deep electrodes: rescue therapy in Parkinson’s disease patients submitted to deep brain stimulation surgery
Objective: Evaluate clinical benefit and safety of unilateral rescue subthalamotomy, concerning motor symptoms in Parkinson’s disease (PD) patients, with partial or total deep brain stimulation…Directional versus conventional subthalamic deep brain stimulation for advanced Parkinson’s disease: Short-term outcomes of a pilot study
Objective: To investigate efficacy of STN-DBS via segmented directional leads compared to conventional omnidirectional leads in PD-patients. Background: Recently, novel leads which allow stimulation steering in…Objective study of intra operative test for discovering optimal electrode site for effective imaging and bilateral STN-DBS stereotactic functional neurosurgery
Objective: The objective is to examine the microrecording(MER, intra operative) and differentiate stimulus induced micro lesion effect on cardinal motor features of Parkinson's disease. Background:…Uptake in Directional Stimulation and Primary Cell Longevity in Deep Brain Stimulation of Globus Pallidus Pars Interna for Parkinson’s Disease
Objective: To retrospectively assess the use of directional programming in deep brain stimulation of globus pallidus pars interna (GPi-DBS) in patients with Parkinson’s disease (PD).…Deep brain stimulation revision from VIM to VIM and PSA severe long-standing refractory ET: case series
Objective: To describe 5 patients with ET who underwent replacement of VIM DBS with leads targeting both VIM and the posterior subthalamic area (PSA) due…KMT2B-related disorders: Expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation
Objective: Clarifying clinical phenotype, molecular genetic features and evolution with deep brain stimulation (DBS) of KMT2B related disease. Background: Heterozygous mutations in KMT2B are associated…Utilization of a Visualization Software Tool for Deep Brain Stimulation Programming in a Subset of Subjects with Parkinson’s Disease Who Participated in the INTREPID Randomized Clinical Trial
Objective: This report will describe the utilization and parameters associated with the use of a new visualization tool for Deep Brain Stimulation (DBS) programming in…Safety and Tolerability of Burst Cycling Deep Brain Stimulation for Freezing of Gait in Parkinson’s Disease
Objective: To determine the safety and tolerability of burst cycling deep brain stimulation (DBS) in Parkinson's disease (PD) patients experiencing freezing of gait (FoG). Background:…Effectiveness of dopaminergic drugs on motor symptoms in Parkinson’s disease patients with deep brain stimulation of subthalamic nucleus
Objective: To compare the effectiveness of dopaminergic drugs on motor symptoms assessed by UPDRS- III in Parkinson’s disease patients pre and post deep brain stimulation…
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