Pilot study incorporating outcome measures after paediatric deep brain stimulation with patient and carer expectations and satisfaction
Objective: To pilot a multi-faceted evaluation framework for paediatric patients undergoing deep brain stimulation (DBS) in a single centre. Background: DBS can be useful for…Monogenic Dystonia and Deep Brain Stimulation: Single Center Experience
Objective: The aim of this study was to retrospectively assess the efficacy of deep brain stimulation in patients with confirmed monogenic dystonia. Background: Treatment of…Effects of combined subthalamic and dorsolateral nigral deep brain stimulation on gait performance in Parkinson’s Disease
Objective: To investigate short-term effects of combined deep brain stimulation (DBS) of the substantia nigra pars reticulata (SNr) and subthalamic nucleus (STN) on gait performance,…Brain-behavior quantification and synchronization to drive closed-loop deep brain stimulation
Objective: Closed-loop DBS systems require a neural biomarker to responsively turn on stimulation, which in turn requires neurophysiological quantification synchronized to behavior or symptoms. Our…local field potential differences in stn subregion during performance of a conflict task in humans with parkinson’s disease
Objective: Examine dorsal and ventral STN subregion's roles in motor conflict with intraoperative recordings during the implantation of a DBS device in Parkinson’s disease (PD)…Hyperkinetic dystonia in dyskinetic cerebral palsy responds to combined DBS stimulation in thalamus and pallidum.
Objective: To describe the response of hyperkinetic dystonia in four pediatric patients with dyskinetic CP to combined DBS stimulation in thalamus and pallidum. Background: Dystonia…Deep brain stimulation modulates subthalamic beta bursts related to movement velocity adjustments in Parkinson’s disease
Objective: The aim of this study was to investigate the role of subthalamic beta bursts for dynamic control of precise drawing movements. Background: The performance…Long-term follow up of Deep Brain Stimulation in Pantothenate Kinase-Associated Neurodegeneration Syndrome: two case reports
Objective: To present the long-term outcomes of deep brain stimulation in two cases of Pantothenate kinase-associated neurodegeneration (PKAN) syndrome. Background: PKAN syndrome is an autosomal-recessive…Investigation of superficial brain stimulation (SBS) in Parkinsonian rats as a non-invasive alternative treatment for patients with movement disorders
Objective: To investigate repetitive transcranial magnetic stimulation (rTMS) in parkinsonian rats as a non-invasive, malleable superficial brain stimulation (SBS) alternative to DBS. Background: DBS is…Effects of Subthalamic Nucleus Deep Brain Stimulation on Phase Amplitude Coupling in Parkinson’s disease
Objective: To investigate the effects of deep brain stimulation (DBS) on neural activity in patients with Parkinson's disease (PD). Specifically, to assess the effects of…
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