Unveiling the Long-term Impact of Unilateral Vim DBS in Essential Tremor
Objective: Our aim is to evaluate the long-term benefit of unilateral VIM DBS. Background: Essential tremor (ET) is the most common movement disorder, and in…Understanding the Neurochemical Basis of STN and GPi-DBS: A Human Microdialysis Study
Objective: Analyze the extracellular concentrations of GABA and glutamate in response to acute electrical stimulation during DBS surgery using samples obtained from STN, thalamus, GPi…Deposition of phosphorylated TDP-43 around the tip of deep brain stimulation leads
Objective: The objective of this study is to investigate the depositions of abnormal proteins, including phosphorylated tau (p-tau) and phosphorylated transactivation response DNA-binding protein of…Effect of Target Selection on Mood, Pain, and Medications after DBS in PD
Objective: To describe the association between medication adjustments with mood and pain following bilateral deep brain stimulation (DBS) in Parkinson’s disease (PD). Background: Depression, anxiety,…Development of a Beta-sensing Pathway in Deep brain stimulation to optimise utility of Local field potential recordings using the Percept system. (Newcastle Beta-sensing Algorithm – NBA)
Objective: To establish a pathway for utilisation of beta-sensing using the Percept technology which is applicable to real world clinical practice and optimises the utility…Bilateral Deep Brain Stimulation in Subthalamic Nucleus versus Globus Pallidus Internus for refractory dystonia
Objective: Evaluate the effects of bilateral Deep Brain Stimulation (DBS) in Subthalamic Nucleus (STN) versus Globus Pallidus Internus (GPi) for patients with refractory dystonia. Background:…Real-Time Removal of Stimulus Artifact for Closed-Loop Deep Brain Stimulation by Synchronized Sample-And-Hold Artifact Blanking (SSAB): Verification in Animal Model
Objective: To develop and validate a real-time stimulus artifact removal analog front-end (AFE) by synchronized sample-and-hold artifact blanking (SSAB) technique with the Parkinsonian minipig model…Differentiating the Local Field Potential Oscillations in Low and Beta Range in Parkinson`s and Dystonic Movement Disorder
Objective: To framework the novel data of subcortical oscillations in Parkinson`s and dystonic patients for the comparison of local field oscillatory (low, beta) influence amongst…Personality of Parkinson’s disease patients may influence the development and evolution of non-motor fluctuations
Objective: to evaluate the impact of personality on non-motor fluctuations (NMFs) in Parkinson’s disease (PD) and on NMFs evolution after dopaminergic treatments or deep brain…Investigation of the Quantitative Impact of T-type Calcium Channels in Subthalamic Nucleus Neurons on Parkinson’s Disease
Objective: Parkinson's disease (PD) might be seen as a classic manifestation of "brain arrhythmias" from a pathological standpoint. This work aims to examine the impact…
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