Upregulated vascular endothelial nitric oxide synthase in Parkinson’s disease cases that have received subthalamic stimulation: A post-mortem evaluation
Objective: Here we measured levels of vascular endothelial nitric oxide synthase (eNOS) expression as a result of high frequency (HF) Deep Brain Stimulation (DBS) of…Clinical characteristics of Parkinson’s disease and essential tremor patients undergoing deep brain stimulation surgery: Five-year data from Columbia University Medical Center (2009 – 2014)
Objective: To compare the clinical characteristics of essential tremor (ET) and Parkinson's disease (PD) patients who underwent deep brain stimulation (DBS) surgery to those of…Comparison of four DBS lead designs under voltage and current operating modes based on patient specific simulations
Objective: To quantitatively compare the spatial extension of the electric field generated by four different lead designs operated under voltage and current modes. Background: Conventional…Improving parkinsonism in DBS poor-responders by surgical lead revision of subthalamic electrodes
Objective: If subthalamic deep brain stimulation (STN-DBS) results in poor symptom control or adverse side effects at low stimulation threshold surgical lead revision for optimal…A pilot study of horizontal current steering with chronically implanted segmented electrodes for STN-DBS in Parkinson’s disease
Objective: To evaluate the effect of horizontal current steering using a chronically implanted segmented lead and multiple independent current source technology on clinical effect and…Employing intraoperative microelectrode recordings during "asleep" deep brain stimulation surgery of the globus pallidus internus in Parkinson’s disease
Objective: To employ a means of implanting DBS leads to the GPi in individuals with Parkinson's disease who are undergoing the surgery under general anesthesia…When DBS can be of benefit in Huntington’s disease
Objective: To report on a patient with HD and disabling truncal dystonia who was treated with bilateral GPi DBS. Background: HD is an autosomal-dominant disorder…Emotional valence and arousal ratings from rewarding and fearful stimuli are not influenced by levodopa in Parkinson’s disease
Objective: To analyze the effects of levodopa on affective ratings of emotional valence and arousal to rewarding, fearful and neutral stimuli in PD patients and…The contribution of the subthalamic nucleus in gait initiation of subjects with Parkinson’s disease
Objective: We investigated the contribution of the subthalamic nucleus (STN) in gait initiation of subjects with Parkinson's disease (PD). Background: Gait initiation is the transient…Single unit activity of globus pallidus during voluntary movements in patients with cervical dystonia
Objective: To reveal the electrophysiological mechanism of voluntary movements with and without neck muscle exertion in patients with cervical dystonia. Background: Globus pallidus, as part…
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