Employing intraoperative microelectrode recordings during "asleep" deep brain stimulation surgery of the globus pallidus internus in Parkinson’s disease
Objective: To employ a means of implanting DBS leads to the GPi in individuals with Parkinson's disease who are undergoing the surgery under general anesthesia…Sweet spot of antidystonic effect in pallidal neurostimulation
Objective: We investigated Volumes of Neural Activation (VNAs) in dystonia subjects under effective bilateral pallidum deep brain stimulation (DBS). We aimed to disentangle the sweet…Quality of life after subthalamic stimulation depends on non-motor symptoms in Parkinson’s disease
Objective: To investigate non-motor symptoms (NMS) to find contributing factors for quality of life (QoL) outcome after subthalamic nucleus (STN) deep brain stimulation (DBS) in…Role of dopamine and GABA during subthalamic and pallidal deep brain stimulation: Evidence of dopamine release during subthalamic Deep Brain Stimulation
Objective: We recorded the single-unit activity of striatal cholinergic interneurons of healthy monkeys during high-frequency stimulation (HFS) of the subthalamic nucleus (STN) and globus pallidus…Globus pallidus interna oscillatory activity differentiates tics from voluntary movements and the Parkinsonian resting state
Objective: To describe local field potential (LFP) characteristics during tic acivity, voluntary activity, and the Parkinsonian resting state. Background: Deep brain stimulation is an emerging…Use of dementia rating scale-II (DRS-II) total score in PD deep brain stimulation (DBS) candidacy determination
Objective: To evaluate utility of the DRS-II Total Score for stratifying cognitive status in PD patients without frank cognitive impairment. Background: The DRS-II, a screening…Improvement of levodopa induced foot dystonia with 60 Hz frequency subthalamic- deep brain stimulation
Objective: To present a case of levodopa induced foot dystonia that improved with 60Hz frequency subthalamic- deep brain stimulation. Background: Deep Brain Stimulation is an…Safety and clinical effects of NTCELL® [immunoprotected (alginate-encapsulated) porcine choroid plexus cells for xenotransplantation] in patients with Parkinson’s disease (PD): 81 to 130 weeks follow-up
Objective: To follow the clinical status of 4 PD patients transplanted with NTCELL out to 81-130 weeks. Background: NTCELL comprises neonatal porcine choroid plexus cells…Effect of unilateral subthalamic deep brain stimulation in highly asymmetric Parkinson’s disease: 7- year follow-up
Objective: To evaluate the long-term outcome of unilateral STN DBS in highly asymmetric patients with PD. Background: Unilateral STN DBS is suggested to be a…Multiple-source current steering in bilateral subthalamic nucleus deep brain stimulation for Parkinson’s disease: Our experience
Objective: To evaluate the efficacy and side effects of a multiple-source, constant-current device in a Latin-American population of patients with PD. Background: Timmermann et al.…