Excellent Non-motor Responses after Bilateral Subthalamic Deep Brain Stimulation in Parkinson’s Disease Patient with SNCA Duplication
Objective: We report a case of Parkinson's disease patient with SNCA duplication, who showed excellent response in both motor and non-motor symptoms after bilateral subthalamic stimulation. Background:…Novel Programming Strategy to Overcome Loss of Efficacy in Essential Tremor
Objective: A review of programming strategies to maintain tremor suppression adequate for functional satisfaction. Background: Deep brain stimulation (DBS) is FDA approved for Essential tremor since…Improvement Observed in Children with combined GPi and VL Thalamus Deep Brain Stimulation for the Treatment of Secondary Dystonia
Objective: To present 5 children with Gpi and VL thalamus Deep-Brain Stimulation for treatment of secondary dystonia. Background: The target for deep brain stimulation (DBS) in…Programming of deep brain stimulators in Parkinson’s disease with early motor complications (EARLYSTIM-study)
Objective: Recently the EARLYSTIM study showed the superior effect of subthalamic stimulation to best medical treatment in Parkinson`s disease with early motor complications. Background: EARLYSTIM…Clinical outcome of subthalamic deep brain stimulation in Parkinson’s disease – The Helsinki experience
Objective: To evaluate the efficacy and adverse effects of subthalamic deep brain stimulation (STN-DBS) in patients with advanced Parkinson's disease (PD) and the possible correlation…Identification of unique metabolite signatures in post-mortem DBS human tissue using LC-HRMS
Objective: Metabolomics is applied to the study of metabolic as well as neurodegenerative diseases. We propose to utilize this technique to detect metabolic changes from…A dopamine-dependent activity of the STN in the control of balance in Parkinson’s disease
Objective: To investigate the activity of the subthalamic nucleus (STN), and its relation to nigro-striatal dopaminergic denervation, in control of balance in Parkinson's disease (PD).…Cognitive outcome in the patients with Parkinson’s disease one year after subthalamic implants in Taiwan
Objective: To demonstrate cognitive outcome after subthalamic deep brain stimulation(DBS) in the patients with Parkinson's disease(PD) in Taiwan. Background: Deep brain stimulation of the subthalamic…A case of thalamic malignant glioma formation in a patient with STN-DBS for Parkinson’s disease
Objective: We present a case of development of malignant glioma (glioblastoma multiforme) in the area adjacent to electrostimulation zone in a patient with chronic STN-DBS,…Effects of deep brain stimulation in the nucleus entopeduncularis on neuronal network activity after apomorphine-induced deficient sensorimotor gating in a rat model
Objective: Deficient sensorimotor gating induced by dopamine receptor agonists is used as an endophenotype for certain neuropsychiatric disorders, such as Tourette´s syndrome (TS), schizophrenia, and…
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