Toward clinical use of electrode localizations in deep brain stimulation therapy
Objective: To develop an open source software capable of performing electrode localizations certified for clinical use in deep brain stimulation therapy. Background: Deep brain stimulation…A cognitive monitoring program for individuals with Parkinson’s disease submitted to deep brain stimulation
Objective: Evaluate the feasibility to serially assess cognitive performance with a new self-administered web-based test after DBS. Background: Deep brain stimulation (DBS) has become the…Impact of the combined depletion of monoamines on the effectiveness of deep brain stimulation of the subthalamic nucleus
Objective: To investigate the involvement of combined depletions of dopamine, norepinephrine and serotonin in the manifestation of motor and non-motor deficits and their impact on…Is awake intraoperative mapping still necessary for bilateral subthalamic stimulation for Parkinson’s disease in a modern surgical environment?
Objective: To study the impact of the absence of awake clinical evaluation during subthalamic nucleus (STN) deep brain stimulation (DBS) on parameters of stimulation and…The subthalamic nucleus activity during gait in Parkinson’s disease
Objective: To investigate the activity of the subthalamic nucleus (STN) during gait in subjects with Parkinson's disease (PD). Background: Gait disturbance is a key component…Effectiveness of bilateral pallidal deep brain stimulation in a patient with dystonia associated to neurodegenerative ataxia: Follow-up to 18 months
Objective: CASE REPORT Background: The dystonia like others movement disorder may be included in neurodegenerative ataxia syndrome, in addition to cerebellar dysfunction. The pallidal stimulation…Serum brain-derived neurotrophic factor as an indication of disease state in parkinsonism and RBD
Objective: Evaluation of peripheral concentrations of brain-derived neurotrophic Factor (BDNF) in patients with Parkinsonian disorders and correlation with clinical measurements of disease progression to elucidate…Quantitative assessment of advanced therapies in Parkinson’s disease using the Parkinson kinetigraph (PKG)
Objective: Our aim was to establish whether objective measurements using the Parkinson's Kinetigraph can detect differences between patients undergoing different advanced therapy with either deep…The effect of uni- and bilateral thalamic deep brain stimulation on speech in patients with essential tremor: Acoustics and intelligibility
Objective: In this study, we investigate the effect of VIM-DBS on speech in ET patients. We compare how uni- vs. bilateral DBS contributes to the…Influence of different spike sorting algorithms on the detection of single unit spiking activity in the subthalamic nucleus of patients with Parkinson’s disease
Objective: To determine the most suitable spike sorting algorithm for intraoperatively recorded extracellular currents in the subthalamic nucleus (STN) of patients with Parkinson's disease (PD).…
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