The effect of uni- and bilateral thalamic deep brain stimulation on speech in patients with essential tremor: Acoustics and intelligibility
Objective: In this study, we investigate the effect of VIM-DBS on speech in ET patients. We compare how uni- vs. bilateral DBS contributes to the…Influence of different spike sorting algorithms on the detection of single unit spiking activity in the subthalamic nucleus of patients with Parkinson’s disease
Objective: To determine the most suitable spike sorting algorithm for intraoperatively recorded extracellular currents in the subthalamic nucleus (STN) of patients with Parkinson's disease (PD).…Combined pallidal and thalamic stimulation for multifocal primary dystonia with prominent writers’ cramp
Objective: When a patient presents with both writer's cramp and other dystonic symptoms, it is unclear which target should be chosen. Multifocal DBS is a…A comparison of deep brain stimulation and continuous intrajejunal levodopa infusion in advanced Parkinson’s disease: The INVEST study
Objective: To compare costs and effectiveness of the therapies DBS and CLI in advanced PD. Background: The therapies deep brain stimulation (DBS) and continuous intrajejunale…Difference between physiologically defined subthalamic nucleus target and final lead placement: Influence in clinical outcome
Objective: To evaluate distance between the physiologically defined subthalamic nucleus (STN) target and final lead placement, and its influence on the clinical outcome at 6…Clinical outcome of subthalamic deep brain stimulation in Parkinson’s disease – The Helsinki experience
Objective: To evaluate the efficacy and adverse effects of subthalamic deep brain stimulation (STN-DBS) in patients with advanced Parkinson's disease (PD) and the possible correlation…Identification of unique metabolite signatures in post-mortem DBS human tissue using LC-HRMS
Objective: Metabolomics is applied to the study of metabolic as well as neurodegenerative diseases. We propose to utilize this technique to detect metabolic changes from…A dopamine-dependent activity of the STN in the control of balance in Parkinson’s disease
Objective: To investigate the activity of the subthalamic nucleus (STN), and its relation to nigro-striatal dopaminergic denervation, in control of balance in Parkinson's disease (PD).…Cognitive outcome in the patients with Parkinson’s disease one year after subthalamic implants in Taiwan
Objective: To demonstrate cognitive outcome after subthalamic deep brain stimulation(DBS) in the patients with Parkinson's disease(PD) in Taiwan. Background: Deep brain stimulation of the subthalamic…A case of thalamic malignant glioma formation in a patient with STN-DBS for Parkinson’s disease
Objective: We present a case of development of malignant glioma (glioblastoma multiforme) in the area adjacent to electrostimulation zone in a patient with chronic STN-DBS,…
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