Local field potential changes during sleep in the PSA of patients with essential tremor
Objective: To investigate changes in local field potential (LFP) activity of the posterior subthalamic area (PSA) in patients with essential tremor (ET) during wakefulness and…Brain responses evoked by thalamic and subthalamic deep brain stimulation
Objective: To reveal how the pattern of evoked responses differs between deep brain stimulation (DBS) of the ventral intermediate nucleus of the thalamus (VIM) and…Classification of Dopaminergic-State and Motor Activity by Theta, Beta and Gamma Activity in Parkinson’s Disease
Objective: To test whether machine learning algorithms are suitable to classify dopamine and behavioral states in Parkinson’s patients (PD). Background: While motor symptoms of PD…Bipolar directional DBS in VIM-stimulated patients
Objective: To compare circular, directional and bipolar stimulation in VIM-implanted PD- and ET-patients regarding effect and side-effect thresholds in a cross-sectional design. Background: So far,…The Interface of advanced therapies as Parkinson’s disease progresses – case reports
Objective: To explore the practical benefits and challenges of adding duodenal levodopa-carbidopa intestinal gel infusion (LCIG) to subthalamic nucleus deep brain stimulation (STN DBS) in…Clinical trial protocol: Restitution of oral transport, penetration and aspiration with nigral stimulation in Parkinson’s disease?
Objective: In this randomized controlled clinical trial, we aim to characterize the differential effect of subthalamic nucleus (STN) or subthalamic nucleus and substantia nigra pars…Corticomuscular and Intermuscular Coherence as a Biomarker of Pallidal Deep Brain Stimulation Efficacy in Dystonia
Objective: To find a biomarker of GPi-DBS efficacy in dystonia. Background: GPi-DBS has been proven effective and safe in medically refractory dystonia. However, the heterogeneity…Comparison of Mattis and MOCA testing for neuropsychological assessment in the preoperative evaluation of subthalamic nucleus stimulation in Parkinson´s disease
Objective: The aim of the current study is to evaluate, whether 1. MOCA (Montreal Cognitive Assessment) and Mattis tests are equivalent in the detection of…Directional DBS: A new algorithm to determine lead rotation
Objective: To establish a pipeline for reliable determination of lead rotation in directional DBS. Background: New directional leads with segmented electrodes are now widely used…Evaluation of apathy before and after subthalamic nucleus deep brain stimulation therapy in advanced Parkinson’s disease patients
Objective: Deep brain stimulation (DBS) has been approved to relieve the motor symptoms of Parkinson's disease (PD) patients when the optimal pharmachologic treatment is unsatisfactory.…
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