Determinants of care partner burden in atypical parkinsonian syndromes
Objective: To understand the determinants of burden among people caring for individuals diagnosed with progressive supranuclear palsy (PSP), corticobasal syndrome (CBS), or multiple system atrophy…Early-onset cortico-basal degeneration (CBD) due to a c.2092G>A MAPT mutation
Objective: To describe a patient with early-onset atypical parkinsonism that evolved to a classic CBD without dementia, associated to a c.2092G>A MAPT mutation Background: Although…Autoimmune encephalitis due to antiglycine antibodies presenting as corticobasal syndrome
Objective: To describe a complex case of atypical parkinsonism compatible with corticobasal syndrome (CBS), associated with autoimmune findings in serum and cerebrospinal fluid (CSF) and…Creutzfeldt-Jakob Disease misdiagnosed as Corticobasal degeneration
Objective: We described clinical, radiologic, and neuropathological findings of a patient with Creutzfeldt-Jakob Disease who presented antemortem with clinical features suggestive of corticobasal degeneration. Background:…The Pistol Sign
Objective: To describe a specific dystonic feature associated with corticobasal degeneration(CBD). Background: Dystonia is common in atypical parkinsonian disorders such as multiple system atrophy, progressive…Atypical parkinsonism syndromes: clinical presentations
Objective: Here, our aim was to identify the characteristics of atypical clinical presentations of atypical parkinsonism syndromes in our cohort and our secondary aim was…18F-Florzolotau PET imaging of tau pathology in the living brain of patients with corticobasal syndrome
Objective: To analyze the topographical patterns of tau pathology in the living brains of patients with CBS using 18F-Florzolotau PET imaging and to examine whether…Identification of a Metabolic Brain Pattern Specific to Corticobasal Degeneration and Its Utility in Differential Diagnosis
Objective: To identify a metabolic brain pattern specific to corticobasal degeneration (CBD) and to develop a machine learning algorithm that can differentiate CBD from other…Atypical Parkinsonian Syndrome with evocative brain MRI imaging. About seven cases.
Objective: The diagnosis of Parkinson's disease and parkinsonian syndromes remains clinically difficult, is based on clinical diagnostic criteria, MRI plays a major role in the…Neurofilament light chain, tau-PET and microglia-PET predict clinical progression in amyloid-negative corticobasal syndrome
Objective: A head-to-head comparison of neuroimaging (tau-PET, microglia-PET, structural MRI) and plasma biomarker Neurofilament light chain (NfL) as prognostic tools for longitudinal clinical trajectories in…
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