Does constipation predict cognitive impairment and dementia in de novo Parkinson’s disease patients? A multi-cohort longitudinal data analysis
Objective: To investigate if constipation predicts the development of cognitive impairment (CI) and dementia in de novo Parkinson’s disease (PD). Background: Constipation is one of…Temporal characterization of motor, gastrointestinal, and behavioral symptoms in a SNCA A53T transgenic mouse model of Parkinson’s disease
Objective: While multiple animal models of Parkinson’s disease (PD) have been developed with varying applicability to different aspects of the disorder, no single model effectively…Association between essential tremor, constipation, and the risk of developing Parkinson’s disease
Objective: To evaluate the association between constipation and the risk of Parkinson’s disease (PD) in patients with a prior history of essential tremor (ET). Background:…Intestinal Methanogen Overgrowth (IMO) More Prevalent than SIBO in Parkinson’s disease with Constipation: Preliminary Results
Objective: Our aim is to quantify the prevalence of small intestinal bacterial overgrowth (SIBO) and intestinal methanogen overgrowth (IMO) in PD subjects with constipation compared…The Presence of Efferent Brain-Gut Neuropathy Correlates with Severe Constipation in Parkinson’s disease
Objective: We aim to correlate brain-gut neuropathy amongst cortico- and lumbosacro-anorecal efferent pathways in PD subjects with severe constipation measured by prospective stool diary. Background:…Intestinal transit in early-moderate Parkinson’s disease correlates with probable RBD – subclinical esophageal dysmotility does not correlate
Objective: To investigate esophageal and intestinal transit times in early-moderate Parkinson's disease (PD) and to study correlations with probable RBD and subjective symptoms. Background: Intraneuronal…Evaluation of Constipation in Patients with Parkinson’s Disease and its Correction
Objective: To evaluate the possible causes of constipation, and to find clear methods to correct the disorder. Background: Constipation is a common problem in Parkinson's…Intestinal nerve damage and gut dysfunction in mouse models of Parkinson’s Disease
Objective: This work aims to investigate gut dysfunction and enteric neuropathy in several mouse models of PD to provide insight into enteric nervous system (ENS)…Functional Bowel Symptoms in Parkinson´s Disease
Objective: We assessed the prevalence of functional bowel disorders in patients with Parkinson´s disease (PD) using Rome III criteria. Background: A significant fraction of PD…MIBG myocardial scintigraphy identifies premotor PD/DLB during a negative DAT scan period
Objective: It is unknown which marker is useful to identify the premotor phase PD/DLB. We recently reported four patients who, during a negative DAT scan…
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